Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)

Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu 2+ L -1 (95% confidence interval: 3.21-4.89); the bioconcentration of the metal after 96 h exposure followed an exponential in...

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Autores principales:	Ossana, N.A., Castañé, P.M., Poletta, G.L., Mudry, M.D., Salibián, A.
Formato:	JOUR
Materias:	Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00074861_v84_n6_p712_Ossana
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00074861_v84_n6_p712_Ossana
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spelling	todo:paper_00074861_v84_n6_p712_Ossana2023-10-03T14:05:45Z Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) Ossana, N.A. Castañé, P.M. Poletta, G.L. Mudry, M.D. Salibián, A. Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu 2+ L -1 (95% confidence interval: 3.21-4.89); the bioconcentration of the metal after 96 h exposure followed an exponential increase. The potential genotoxicity effect evaluated with Micronucleus Test showed a reduced sensitivity of the animals to the assayed concentrations of the metal, exhibiting only a modest increase in the frequency of erythrocytes micronuclei, meanwhile larvae exposed to cyclophosphamide (positive control) showed significant increases. The Condition Factor was significantly reduced while the Hepatosomatic Index remained unaltered. © 2010 Springer Science+Business Media, LLC. Fil:Ossana, N.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Poletta, G.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mudry, M.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00074861_v84_n6_p712_Ossana
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates
spellingShingle	Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates Ossana, N.A. Castañé, P.M. Poletta, G.L. Mudry, M.D. Salibián, A. Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
topic_facet	Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates
description	Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu 2+ L -1 (95% confidence interval: 3.21-4.89); the bioconcentration of the metal after 96 h exposure followed an exponential increase. The potential genotoxicity effect evaluated with Micronucleus Test showed a reduced sensitivity of the animals to the assayed concentrations of the metal, exhibiting only a modest increase in the frequency of erythrocytes micronuclei, meanwhile larvae exposed to cyclophosphamide (positive control) showed significant increases. The Condition Factor was significantly reduced while the Hepatosomatic Index remained unaltered. © 2010 Springer Science+Business Media, LLC.
format	JOUR
author	Ossana, N.A. Castañé, P.M. Poletta, G.L. Mudry, M.D. Salibián, A.
author_facet	Ossana, N.A. Castañé, P.M. Poletta, G.L. Mudry, M.D. Salibián, A.
author_sort	Ossana, N.A.
title	Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
title_short	Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
title_full	Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
title_fullStr	Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
title_full_unstemmed	Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
title_sort	toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (shaw, 1802)
url	http://hdl.handle.net/20.500.12110/paper_00074861_v84_n6_p712_Ossana
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Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)

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