Distinctive cognate sequence discrimination, bound DNA conformation, and binding modes in the E2 C-terminal domains from prototype human and bovine papillomaviruses

The C-terminal DNA binding domain of the E2 protein is involved in transcriptional regulation and DNA replication in papillomaviruses. At low ionic strength, the domain has a tendency to form aggregates, a process readily reversible by the addition of salt. While fluorescence anisotropy measurements...

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Autores principales: Ferreiro, D.U., Lima, L.M.T.R., Nadra, A.D., Alonso, L.G., Goldbaum, F.A., De Prat-Gay, G.
Formato: JOUR
Materias:
DNA
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00062960_v39_n47_p14692_Ferreiro
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