A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity
A Neurospora crassa morphological mutation at the crisp locus is related to a low specific activity of adenylate cyclase. This observation was made in two different strains: FGSC No. 329 and FGSC No. 326, both carrying the crisp mutation (allele N. B 123). Crosses of these strains to others having t...
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todo:paper_0006291X_v58_n4_p990_Terenzi2023-10-03T14:04:06Z A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity Terenzi, H.F. Flawiá, M.M. Torres, H.N. adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity A Neurospora crassa morphological mutation at the crisp locus is related to a low specific activity of adenylate cyclase. This observation was made in two different strains: FGSC No. 329 and FGSC No. 326, both carrying the crisp mutation (allele N. B 123). Crosses of these strains to others having the wild type allele yield isolates with the crisp phenotype all of them having low adenylate cyclase specific activity in crude extracts. The other phenotypes obtained showed wild type levels of specific activity. Addition of 3′, 5′ dibutyryl cyclic AMP to the FGSC No. 329 cultures increased four-fold mycelial growth rate and stimulated the formation of aerial hyphae. Simultaneously, uniform conidiation on the surface of the slant was inhibited by the cyclic AMP derivative. © 1974 Academic Press, Inc. Fil:Flawiá, M.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Torres, H.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0006291X_v58_n4_p990_Terenzi |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity |
| spellingShingle |
adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity Terenzi, H.F. Flawiá, M.M. Torres, H.N. A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| topic_facet |
adenylate cyclase bucladesine fungus genetics growth in vitro study microorganism neurospora crassa theoretical study Adenosine Monophosphate Adenylate Cyclase Alleles Bucladesine Butyrates Chromosome Mapping Comparative Study Crosses, Genetic Cyclic AMP Genotype Mutation Neurospora Neurospora crassa Phenotype Species Specificity |
| description |
A Neurospora crassa morphological mutation at the crisp locus is related to a low specific activity of adenylate cyclase. This observation was made in two different strains: FGSC No. 329 and FGSC No. 326, both carrying the crisp mutation (allele N. B 123). Crosses of these strains to others having the wild type allele yield isolates with the crisp phenotype all of them having low adenylate cyclase specific activity in crude extracts. The other phenotypes obtained showed wild type levels of specific activity. Addition of 3′, 5′ dibutyryl cyclic AMP to the FGSC No. 329 cultures increased four-fold mycelial growth rate and stimulated the formation of aerial hyphae. Simultaneously, uniform conidiation on the surface of the slant was inhibited by the cyclic AMP derivative. © 1974 Academic Press, Inc. |
| format |
JOUR |
| author |
Terenzi, H.F. Flawiá, M.M. Torres, H.N. |
| author_facet |
Terenzi, H.F. Flawiá, M.M. Torres, H.N. |
| author_sort |
Terenzi, H.F. |
| title |
A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| title_short |
A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| title_full |
A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| title_fullStr |
A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| title_full_unstemmed |
A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| title_sort |
neurospora crassa morphological mutant showing reduced adenylate cyclase activity |
| url |
http://hdl.handle.net/20.500.12110/paper_0006291X_v58_n4_p990_Terenzi |
| work_keys_str_mv |
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1782023625757425664 |