The role of dolichol monophosphate in sugar transfer

The specificity of the transfer of monosaccharides from sugar nucleotides to dolichol monophosphate catalyzed by liver microsomes was studied. Besides uridine diphosphate glucose, uridine diphosphate-N-acetylglucosamine and guanosine diphosphate mannose were found to act as donors for the formation...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Behrens, N.H., Parodi, A.J., Leloir, L.F., Krisman, C.R.
Formato:	JOUR
Materias:	alkene amino acid bile acid cerebroside collagen fatty acid galactose glucosamine glucose glycol guanine nucleotide hexosamine hexose mannose nucleoside diphosphate sugar nucleotide organophosphorus compound phosphoric acid polymer pyrimidine nucleotide Surface Active Agents surfactant animal article brain catalysis drug stability enzymology liver microsome metabolism pH rat skin solubility temperature thin layer chromatography Alkenes Amino Acids Animal Animals, Newborn Bile Acids and Salts Brain Catalysis Cerebrosides Chromatography, Thin Layer Collagen Drug Stability Fatty Acids Galactose Glucosamine Glucose Glycols Guanine Nucleotides Hexosamines Hexoses Hydrogen-Ion Concentration Mannose Microsomes, Liver Nucleoside Diphosphate Sugars Nucleotides Organophosphorus Compounds Phosphoric Acids Polymers Rats Skin Solubility Surface-Active Agents Temperature Uracil Nucleotides
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00039861_v143_n2_p375_Behrens
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00039861_v143_n2_p375_Behrens
record_format	dspace
spelling	todo:paper_00039861_v143_n2_p375_Behrens2023-10-03T13:56:51Z The role of dolichol monophosphate in sugar transfer Behrens, N.H. Parodi, A.J. Leloir, L.F. Krisman, C.R. alkene amino acid bile acid cerebroside collagen fatty acid galactose glucosamine glucose glycol guanine nucleotide hexosamine hexose mannose nucleoside diphosphate sugar nucleotide organophosphorus compound phosphoric acid polymer pyrimidine nucleotide Surface Active Agents surfactant animal article brain catalysis drug stability enzymology liver microsome metabolism pH rat skin solubility temperature thin layer chromatography Alkenes Amino Acids Animal Animals, Newborn Bile Acids and Salts Brain Catalysis Cerebrosides Chromatography, Thin Layer Collagen Drug Stability Fatty Acids Galactose Glucosamine Glucose Glycols Guanine Nucleotides Hexosamines Hexoses Hydrogen-Ion Concentration Mannose Microsomes, Liver Nucleoside Diphosphate Sugars Nucleotides Organophosphorus Compounds Phosphoric Acids Polymers Rats Skin Solubility Surface-Active Agents Temperature Uracil Nucleotides The specificity of the transfer of monosaccharides from sugar nucleotides to dolichol monophosphate catalyzed by liver microsomes was studied. Besides uridine diphosphate glucose, uridine diphosphate-N-acetylglucosamine and guanosine diphosphate mannose were found to act as donors for the formation of the respective dolichol monophosphate sugars. Uridine diphosphate galactose and uridine diphosphate-N-acetylgalactosamine gave negative results. The optimal conditions for transfer from dolichol monophosphate glucose to endogenous acceptor was determined. Studies were carried out on the glucosylation of ceramide by brain extracts and of collagen by skin enzymes in order to find out if dolichol monophosphate glucose is an intermediate in these reactions. The results, while not definite, were not in favor of this assumption. © 1971. Fil:Behrens, N.H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Parodi, A.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Krisman, C.R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00039861_v143_n2_p375_Behrens
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	alkene amino acid bile acid cerebroside collagen fatty acid galactose glucosamine glucose glycol guanine nucleotide hexosamine hexose mannose nucleoside diphosphate sugar nucleotide organophosphorus compound phosphoric acid polymer pyrimidine nucleotide Surface Active Agents surfactant animal article brain catalysis drug stability enzymology liver microsome metabolism pH rat skin solubility temperature thin layer chromatography Alkenes Amino Acids Animal Animals, Newborn Bile Acids and Salts Brain Catalysis Cerebrosides Chromatography, Thin Layer Collagen Drug Stability Fatty Acids Galactose Glucosamine Glucose Glycols Guanine Nucleotides Hexosamines Hexoses Hydrogen-Ion Concentration Mannose Microsomes, Liver Nucleoside Diphosphate Sugars Nucleotides Organophosphorus Compounds Phosphoric Acids Polymers Rats Skin Solubility Surface-Active Agents Temperature Uracil Nucleotides
spellingShingle	alkene amino acid bile acid cerebroside collagen fatty acid galactose glucosamine glucose glycol guanine nucleotide hexosamine hexose mannose nucleoside diphosphate sugar nucleotide organophosphorus compound phosphoric acid polymer pyrimidine nucleotide Surface Active Agents surfactant animal article brain catalysis drug stability enzymology liver microsome metabolism pH rat skin solubility temperature thin layer chromatography Alkenes Amino Acids Animal Animals, Newborn Bile Acids and Salts Brain Catalysis Cerebrosides Chromatography, Thin Layer Collagen Drug Stability Fatty Acids Galactose Glucosamine Glucose Glycols Guanine Nucleotides Hexosamines Hexoses Hydrogen-Ion Concentration Mannose Microsomes, Liver Nucleoside Diphosphate Sugars Nucleotides Organophosphorus Compounds Phosphoric Acids Polymers Rats Skin Solubility Surface-Active Agents Temperature Uracil Nucleotides Behrens, N.H. Parodi, A.J. Leloir, L.F. Krisman, C.R. The role of dolichol monophosphate in sugar transfer
topic_facet	alkene amino acid bile acid cerebroside collagen fatty acid galactose glucosamine glucose glycol guanine nucleotide hexosamine hexose mannose nucleoside diphosphate sugar nucleotide organophosphorus compound phosphoric acid polymer pyrimidine nucleotide Surface Active Agents surfactant animal article brain catalysis drug stability enzymology liver microsome metabolism pH rat skin solubility temperature thin layer chromatography Alkenes Amino Acids Animal Animals, Newborn Bile Acids and Salts Brain Catalysis Cerebrosides Chromatography, Thin Layer Collagen Drug Stability Fatty Acids Galactose Glucosamine Glucose Glycols Guanine Nucleotides Hexosamines Hexoses Hydrogen-Ion Concentration Mannose Microsomes, Liver Nucleoside Diphosphate Sugars Nucleotides Organophosphorus Compounds Phosphoric Acids Polymers Rats Skin Solubility Surface-Active Agents Temperature Uracil Nucleotides
description	The specificity of the transfer of monosaccharides from sugar nucleotides to dolichol monophosphate catalyzed by liver microsomes was studied. Besides uridine diphosphate glucose, uridine diphosphate-N-acetylglucosamine and guanosine diphosphate mannose were found to act as donors for the formation of the respective dolichol monophosphate sugars. Uridine diphosphate galactose and uridine diphosphate-N-acetylgalactosamine gave negative results. The optimal conditions for transfer from dolichol monophosphate glucose to endogenous acceptor was determined. Studies were carried out on the glucosylation of ceramide by brain extracts and of collagen by skin enzymes in order to find out if dolichol monophosphate glucose is an intermediate in these reactions. The results, while not definite, were not in favor of this assumption. © 1971.
format	JOUR
author	Behrens, N.H. Parodi, A.J. Leloir, L.F. Krisman, C.R.
author_facet	Behrens, N.H. Parodi, A.J. Leloir, L.F. Krisman, C.R.
author_sort	Behrens, N.H.
title	The role of dolichol monophosphate in sugar transfer
title_short	The role of dolichol monophosphate in sugar transfer
title_full	The role of dolichol monophosphate in sugar transfer
title_fullStr	The role of dolichol monophosphate in sugar transfer
title_full_unstemmed	The role of dolichol monophosphate in sugar transfer
title_sort	role of dolichol monophosphate in sugar transfer
url	http://hdl.handle.net/20.500.12110/paper_00039861_v143_n2_p375_Behrens
work_keys_str_mv	AT behrensnh theroleofdolicholmonophosphateinsugartransfer AT parodiaj theroleofdolicholmonophosphateinsugartransfer AT leloirlf theroleofdolicholmonophosphateinsugartransfer AT krismancr theroleofdolicholmonophosphateinsugartransfer AT behrensnh roleofdolicholmonophosphateinsugartransfer AT parodiaj roleofdolicholmonophosphateinsugartransfer AT leloirlf roleofdolicholmonophosphateinsugartransfer AT krismancr roleofdolicholmonophosphateinsugartransfer
_version_	1807324461202931712

The role of dolichol monophosphate in sugar transfer

Ejemplares similares