Quantum dots as ultrasensitive nanoactuators and sensors of amyloid aggregation in live cells

Quantum dots multifunctionalized with the amyloid protein α-synuclein act at nanomolar concentrations as very potent inducers of the aggregation of micromolar-millimolar bulk concentrations of the protein in vitro and in cells. Fibrillation in live cells, a process diagnostic of Parkinson's dis...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Roberti, M.J., Morgan, M., Menéndez, G., Pietrasanta, L.I., Jovin, T.M., Jares-Erijman, E.A.
Formato: JOUR
Materias:
Amyloid formation
Amyloid proteins
Bulk concentration
Fluorogenic
In-cell
In-vitro
Live cell
Nanoactuators
Nanomolar concentration
Parkinson's disease
Process diagnostics
Quantum Dot
Sensitive systems
Synuclein
Ultrasensitive
Glycoproteins
Semiconductor quantum dots
Cell membranes
alpha synuclein
amyloid
amyloid protein
nanoparticle
quantum dot
fluorescent dye
article
atomic force microscopy
concentration (parameters)
female
fluorescence microscopy
human
human cell
in vitro study
molecular mechanics
nanosensor
Parkinson disease
protein aggregation
quantum mechanics
chemistry
genetic procedures
HeLa cell
metabolism
alpha-Synuclein
Amyloid
Biosensing Techniques
Fluorescent Dyes
Hela Cells
Humans
Microscopy, Atomic Force
Microscopy, Fluorescence
Quantum Dots
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00027863_v131_n23_p8102_Roberti
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares