In vitro effect of 5-fluorouracil and paclitaxel on Echinococcus granulosus larvae and cells

Human cystic echinococcosis is a zoonosis caused by the metacestode stage of the tapeworm Echinococcus granulosus. Although benzimidazole compounds such as albendazole and mebendazole have been the cornerstone of chemotherapy for the disease, there is often no complete recovery after treatment. Henc...

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Detalles Bibliográficos
Autores principales: Pensel, P.E., Albani, C., Gamboa, G.U., Benoit, J.P., Elissondo, M.C.
Formato: JOUR
Materias:
5-Fluorouracilo
Cyst echinococcosis
Echinococcus granulosus
Hydatid cysts
Paclitaxel
fluorouracil
paclitaxel
anticestodal agent
cyst
drug
echinococcosis
efficiency measurement
experiment
laboratory method
larva
parasite
survival
time dependent behavior
cell organelle
chemotherapy
disease treatment
incubation
inoculation
parasite infestation
animal cell
animal experiment
animal model
animal tissue
antiparasitic activity
article
cell growth
cell survival
cell type
cestode germinal cell
concentration response
controlled study
drug activity
drug efficacy
female
growth inhibition
in vitro study
metacestode
mouse
nonhuman
parasite viability
protoscolex
scanning electron microscopy
scolex
transmission electron microscopy
animal
dose response
drug effects
inbred mouse strain
anthelmintic activity
Article
drug effect
parasite survival
parasite virulence
Animals
Anticestodal Agents
Dose-Response Relationship, Drug
Echinococcosis
Female
Fluorouracil
In Vitro Techniques
Larva
Mice
Mice, Inbred Strains
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0001706X_v140_n_p1_Pensel
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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