A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy

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We have described a method for preparation of [10B]-enriched-8- dihydroxyborylharmine (III) and characterized it by their spectral properties (MS, IR and NMR). This compound is a potential BNCT agent.

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Detalles Bibliográficos
Autores principales: Sintas, J.A., Macareno, N.J., Vitale, A.A.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2000
Materias:
8 dihydroxyborylharmine b 10
radiopharmaceutical agent
unclassified drug
animal tissue
autoradiography
binding site
conference paper
drug distribution
drug structure
drug synthesis
neutron capture therapy
nonhuman
rat
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14203049_v5_n3_p526_Sintas
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling paperaa:paper_14203049_v5_n3_p526_Sintas2023-06-12T16:50:05Z A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy Molecules 2000;5(3):526-528 Sintas, J.A. Macareno, N.J. Vitale, A.A. 8 dihydroxyborylharmine b 10 radiopharmaceutical agent unclassified drug animal tissue autoradiography binding site conference paper drug distribution drug structure drug synthesis neutron capture therapy nonhuman rat We have described a method for preparation of [10B]-enriched-8- dihydroxyborylharmine (III) and characterized it by their spectral properties (MS, IR and NMR). This compound is a potential BNCT agent. Fil:Vitale, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2000 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion application/pdf eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_14203049_v5_n3_p526_Sintas
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
language Inglés
orig_language_str_mv eng
topic 8 dihydroxyborylharmine b 10
radiopharmaceutical agent
unclassified drug
animal tissue
autoradiography
binding site
conference paper
drug distribution
drug structure
drug synthesis
neutron capture therapy
nonhuman
rat
spellingShingle 8 dihydroxyborylharmine b 10
radiopharmaceutical agent
unclassified drug
animal tissue
autoradiography
binding site
conference paper
drug distribution
drug structure
drug synthesis
neutron capture therapy
nonhuman
rat
Sintas, J.A.
Macareno, N.J.
Vitale, A.A.
A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
topic_facet 8 dihydroxyborylharmine b 10
radiopharmaceutical agent
unclassified drug
animal tissue
autoradiography
binding site
conference paper
drug distribution
drug structure
drug synthesis
neutron capture therapy
nonhuman
rat
description We have described a method for preparation of [10B]-enriched-8- dihydroxyborylharmine (III) and characterized it by their spectral properties (MS, IR and NMR). This compound is a potential BNCT agent.
format Artículo
Artículo
publishedVersion
author Sintas, J.A.
Macareno, N.J.
Vitale, A.A.
author_facet Sintas, J.A.
Macareno, N.J.
Vitale, A.A.
author_sort Sintas, J.A.
title A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
title_short A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
title_full A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
title_fullStr A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
title_full_unstemmed A facile high-yield synthesis of [10B]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
title_sort facile high-yield synthesis of [10b]-8-dihydroxyboryl harmine, a potential agent for boron neutron capture therapy
publishDate 2000
url http://hdl.handle.net/20.500.12110/paper_14203049_v5_n3_p526_Sintas
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