Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties

Polymeric materials having biomedical applications can be classified into two major groups according to their use: those employed in prosthetic devices, such as cardiovascular and orthopedic prostheses; and those employed as therapeutic systems, such as drug carriers. Among prosthetic systems, polym...

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Detalles Bibliográficos
Publicado:	2015
Materias:	Bone-tissue engineering Cardiovascular-tissue engineering Medical device Specific drug administration Biocompatibility Biomechanics Bone Chemical properties Diagnosis Esters Medical applications Prosthetics Tissue Tissue engineering Biomedical applications Bone tissue engineering Cardiovascular tissue engineering Drug administration Medical Devices Orthopedic prosthesis Physical and chemical properties Therapeutic treatments Functional polymers
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97811190_v1_n_p369_Parisi http://hdl.handle.net/20.500.12110/paper_97811190_v1_n_p369_Parisi
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_97811190_v1_n_p369_Parisi
record_format	dspace
spelling	paper:paper_97811190_v1_n_p369_Parisi2023-06-08T16:37:13Z Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties Bone-tissue engineering Cardiovascular-tissue engineering Medical device Specific drug administration Biocompatibility Biomechanics Bone Chemical properties Diagnosis Esters Medical applications Prosthetics Tissue Tissue engineering Biomedical applications Bone tissue engineering Cardiovascular tissue engineering Drug administration Medical Devices Orthopedic prosthesis Physical and chemical properties Therapeutic treatments Functional polymers Polymeric materials having biomedical applications can be classified into two major groups according to their use: those employed in prosthetic devices, such as cardiovascular and orthopedic prostheses; and those employed as therapeutic systems, such as drug carriers. Among prosthetic systems, polymeric materials can be used as coatings or as cemented prostheses. Some of the major advantages in using polymeric materials for biomedical applications are their flexibility, biocompatibility, the possibility of tailoring their mechanical properties and their ability to incorporate therapeutic agents into their matrix in order to allow drug administration at a specific site. The aim of this chapter is to summarize the uses and applications in the field of medical devices, as well as to discuss the pharmaceutical, physical and chemical properties of two of the most popular biomedical polymers: poly(methyl methacrylate) and polyurethanes (PU). In particular, we will center our attention on their use as site-specific drug administration and their application in two great areas of prosthetic devices, bone tissue and cardiovascular engineering. We will also cover their use in diagnosis and in therapeutic treatments along with advances and future perspectives in both areas. © 2015 Scrivener Publishing LLC. All rights reserved. 2015 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97811190_v1_n_p369_Parisi http://hdl.handle.net/20.500.12110/paper_97811190_v1_n_p369_Parisi
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Bone-tissue engineering Cardiovascular-tissue engineering Medical device Specific drug administration Biocompatibility Biomechanics Bone Chemical properties Diagnosis Esters Medical applications Prosthetics Tissue Tissue engineering Biomedical applications Bone tissue engineering Cardiovascular tissue engineering Drug administration Medical Devices Orthopedic prosthesis Physical and chemical properties Therapeutic treatments Functional polymers
spellingShingle	Bone-tissue engineering Cardiovascular-tissue engineering Medical device Specific drug administration Biocompatibility Biomechanics Bone Chemical properties Diagnosis Esters Medical applications Prosthetics Tissue Tissue engineering Biomedical applications Bone tissue engineering Cardiovascular tissue engineering Drug administration Medical Devices Orthopedic prosthesis Physical and chemical properties Therapeutic treatments Functional polymers Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
topic_facet	Bone-tissue engineering Cardiovascular-tissue engineering Medical device Specific drug administration Biocompatibility Biomechanics Bone Chemical properties Diagnosis Esters Medical applications Prosthetics Tissue Tissue engineering Biomedical applications Bone tissue engineering Cardiovascular tissue engineering Drug administration Medical Devices Orthopedic prosthesis Physical and chemical properties Therapeutic treatments Functional polymers
description	Polymeric materials having biomedical applications can be classified into two major groups according to their use: those employed in prosthetic devices, such as cardiovascular and orthopedic prostheses; and those employed as therapeutic systems, such as drug carriers. Among prosthetic systems, polymeric materials can be used as coatings or as cemented prostheses. Some of the major advantages in using polymeric materials for biomedical applications are their flexibility, biocompatibility, the possibility of tailoring their mechanical properties and their ability to incorporate therapeutic agents into their matrix in order to allow drug administration at a specific site. The aim of this chapter is to summarize the uses and applications in the field of medical devices, as well as to discuss the pharmaceutical, physical and chemical properties of two of the most popular biomedical polymers: poly(methyl methacrylate) and polyurethanes (PU). In particular, we will center our attention on their use as site-specific drug administration and their application in two great areas of prosthetic devices, bone tissue and cardiovascular engineering. We will also cover their use in diagnosis and in therapeutic treatments along with advances and future perspectives in both areas. © 2015 Scrivener Publishing LLC. All rights reserved.
title	Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_short	Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_full	Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_fullStr	Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_full_unstemmed	Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties
title_sort	polymeric prosthetic systems for site-specific drug administration: physical and chemical properties
publishDate	2015
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97811190_v1_n_p369_Parisi http://hdl.handle.net/20.500.12110/paper_97811190_v1_n_p369_Parisi
_version_	1768543011051929600

Polymeric Prosthetic Systems for Site-Specific Drug Administration: Physical and Chemical Properties

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