Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)

In the present work, controlled experimental infection and transmission studies in domestic cattle (Bos taurus) and water buffaloes (Bubalus bubalis) were carried out to study the in vivo behaviour of bubaline herpesvirus 1 (BuHV1). Two bovine and two buffalo calves were infected with BuHV1 (20287N...

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Publicado: 2016
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_23992050_v3_n1_p_Maidana
http://hdl.handle.net/20.500.12110/paper_23992050_v3_n1_p_Maidana
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_23992050_v3_n1_p_Maidana
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spelling paper:paper_23992050_v3_n1_p_Maidana2023-06-08T16:35:55Z Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1) In the present work, controlled experimental infection and transmission studies in domestic cattle (Bos taurus) and water buffaloes (Bubalus bubalis) were carried out to study the in vivo behaviour of bubaline herpesvirus 1 (BuHV1). Two bovine and two buffalo calves were infected with BuHV1 (20287N isolate) by intranasal aerosolisation. Two sentinel cattle did not receive the virus challenge, but were housed with infected buffaloes to evaluate horizontal transmission. All experimentally inoculated animals showed viral infection and respiratory clinical signs. BuHV1 experimentally infected calves showed intermittent viral excretion between 2 days and 18 days postinfection (dpi) with a maximum titre of excretion of 106 TCID50/ ml and moderate rhinitis between 2 dpi and 20 dpi. BuHV1 experimentally inoculated buffaloes showed mild respiratory signs, which consisted mainly of serous nasal secretions during the infection period. Sentinel calves showed mucosal specific IgG1 antibodies at seven days postcontact. Viral DNA was detected by PCR and sequencing in both buffaloes and sentinel calves, which could be associated with latency. In conclusion, this study showed the susceptibility of cattle to BuHV1 after both experimental infection and contact with infected buffaloes. These data increase the scarce knowledge on the pathogenesis in natural host and the susceptibility of cattle to BuHV1 experimental infection. © 2016 Veterinary Record Open. All rights reserved. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_23992050_v3_n1_p_Maidana http://hdl.handle.net/20.500.12110/paper_23992050_v3_n1_p_Maidana
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description In the present work, controlled experimental infection and transmission studies in domestic cattle (Bos taurus) and water buffaloes (Bubalus bubalis) were carried out to study the in vivo behaviour of bubaline herpesvirus 1 (BuHV1). Two bovine and two buffalo calves were infected with BuHV1 (20287N isolate) by intranasal aerosolisation. Two sentinel cattle did not receive the virus challenge, but were housed with infected buffaloes to evaluate horizontal transmission. All experimentally inoculated animals showed viral infection and respiratory clinical signs. BuHV1 experimentally infected calves showed intermittent viral excretion between 2 days and 18 days postinfection (dpi) with a maximum titre of excretion of 106 TCID50/ ml and moderate rhinitis between 2 dpi and 20 dpi. BuHV1 experimentally inoculated buffaloes showed mild respiratory signs, which consisted mainly of serous nasal secretions during the infection period. Sentinel calves showed mucosal specific IgG1 antibodies at seven days postcontact. Viral DNA was detected by PCR and sequencing in both buffaloes and sentinel calves, which could be associated with latency. In conclusion, this study showed the susceptibility of cattle to BuHV1 after both experimental infection and contact with infected buffaloes. These data increase the scarce knowledge on the pathogenesis in natural host and the susceptibility of cattle to BuHV1 experimental infection. © 2016 Veterinary Record Open. All rights reserved.
title Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)
spellingShingle Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)
title_short Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)
title_full Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)
title_fullStr Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)
title_full_unstemmed Cattle are a potential reservoir of bubaline herpesvirus 1 (BuHV1)
title_sort cattle are a potential reservoir of bubaline herpesvirus 1 (buhv1)
publishDate 2016
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_23992050_v3_n1_p_Maidana
http://hdl.handle.net/20.500.12110/paper_23992050_v3_n1_p_Maidana
_version_ 1768543822823817216

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