The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity
Dendritic cell (DC) cancer vaccines have shown limited clinical benefit. Thus, the identification of signals and molecular pathways that potentiate the immunogenicity of DCs has become a major challenge in cancer research. Our studies demonstrate that triiodothyronine endows DCs with enhanced abilit...
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2016
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_21624011_v5_n1_p_Alamino http://hdl.handle.net/20.500.12110/paper_21624011_v5_n1_p_Alamino |
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paper:paper_21624011_v5_n1_p_Alamino2023-06-08T16:34:31Z The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity Cancer vaccination Dendritic cell Immunotherapy Thyroid hormone Triiodothyronine cancer vaccine gamma interferon liothyronine Article cell differentiation cross presentation dendritic cell immune response immunogenicity nonhuman protein expression signal transduction tumor growth tumor immunity Dendritic cell (DC) cancer vaccines have shown limited clinical benefit. Thus, the identification of signals and molecular pathways that potentiate the immunogenicity of DCs has become a major challenge in cancer research. Our studies demonstrate that triiodothyronine endows DCs with enhanced ability to stimulate cytotoxic T-cell responses with implications in DC-based immunotherapy. © 2016 Taylor & Francis Group, LLC. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_21624011_v5_n1_p_Alamino http://hdl.handle.net/20.500.12110/paper_21624011_v5_n1_p_Alamino |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Cancer vaccination Dendritic cell Immunotherapy Thyroid hormone Triiodothyronine cancer vaccine gamma interferon liothyronine Article cell differentiation cross presentation dendritic cell immune response immunogenicity nonhuman protein expression signal transduction tumor growth tumor immunity |
| spellingShingle |
Cancer vaccination Dendritic cell Immunotherapy Thyroid hormone Triiodothyronine cancer vaccine gamma interferon liothyronine Article cell differentiation cross presentation dendritic cell immune response immunogenicity nonhuman protein expression signal transduction tumor growth tumor immunity The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| topic_facet |
Cancer vaccination Dendritic cell Immunotherapy Thyroid hormone Triiodothyronine cancer vaccine gamma interferon liothyronine Article cell differentiation cross presentation dendritic cell immune response immunogenicity nonhuman protein expression signal transduction tumor growth tumor immunity |
| description |
Dendritic cell (DC) cancer vaccines have shown limited clinical benefit. Thus, the identification of signals and molecular pathways that potentiate the immunogenicity of DCs has become a major challenge in cancer research. Our studies demonstrate that triiodothyronine endows DCs with enhanced ability to stimulate cytotoxic T-cell responses with implications in DC-based immunotherapy. © 2016 Taylor & Francis Group, LLC. |
| title |
The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| title_short |
The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| title_full |
The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| title_fullStr |
The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| title_full_unstemmed |
The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| title_sort |
thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity |
| publishDate |
2016 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_21624011_v5_n1_p_Alamino http://hdl.handle.net/20.500.12110/paper_21624011_v5_n1_p_Alamino |
| _version_ |
1768544105769467904 |