Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters

There is still an international need to develop broad-spectrum sunscreen products with an adequate UVB/UVA balance, while the approved filters available in the UVA are scarce. Currently, one of the few UVA filters approved in the United States and Europe is tert-butylmethoxydibenzoylmethane (BMDM, a...

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Detalles Bibliográficos
Publicado: 2018
Materias:
Chalcones
Dibenzoylmethanes
Photo-stability
UVA filters
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20799284_v5_n2_p_Lazopulos
http://hdl.handle.net/20.500.12110/paper_20799284_v5_n2_p_Lazopulos
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_20799284_v5_n2_p_Lazopulos
record_format dspace
spelling paper:paper_20799284_v5_n2_p_Lazopulos2023-06-08T16:34:16Z Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters Chalcones Dibenzoylmethanes Photo-stability UVA filters There is still an international need to develop broad-spectrum sunscreen products with an adequate UVB/UVA balance, while the approved filters available in the UVA are scarce. Currently, one of the few UVA filters approved in the United States and Europe is tert-butylmethoxydibenzoylmethane (BMDM, avobenzone). However, this compound is unstable from aphotochemical point of view and cannot be used in combination with certain sunscreens. In this paper, we investigate the photochemical behavior of a set of dibenzoylmethanes and chalcones. In particular, we carry out their absorption and emission spectra, evaluate their photochemical degradation, and study their generation of free radicals and singlet oxygen photoproduction. Two compounds resultedin having the basic properties of UVA filters (2'-hydroxy-4-methoxychalcone and 2'-hydroxy-4-methoxydibenzoylmethane). Further studies are proposed, such as formulating the compounds into emulsions or other common cosmetic presentations, as well as combining them with broadly-used UVB filters. We have also considered the need to establish its toxicological profile. © 2018 by the authors. 2018 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20799284_v5_n2_p_Lazopulos http://hdl.handle.net/20.500.12110/paper_20799284_v5_n2_p_Lazopulos
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Chalcones
Dibenzoylmethanes
Photo-stability
UVA filters
spellingShingle Chalcones
Dibenzoylmethanes
Photo-stability
UVA filters
Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters
topic_facet Chalcones
Dibenzoylmethanes
Photo-stability
UVA filters
description There is still an international need to develop broad-spectrum sunscreen products with an adequate UVB/UVA balance, while the approved filters available in the UVA are scarce. Currently, one of the few UVA filters approved in the United States and Europe is tert-butylmethoxydibenzoylmethane (BMDM, avobenzone). However, this compound is unstable from aphotochemical point of view and cannot be used in combination with certain sunscreens. In this paper, we investigate the photochemical behavior of a set of dibenzoylmethanes and chalcones. In particular, we carry out their absorption and emission spectra, evaluate their photochemical degradation, and study their generation of free radicals and singlet oxygen photoproduction. Two compounds resultedin having the basic properties of UVA filters (2'-hydroxy-4-methoxychalcone and 2'-hydroxy-4-methoxydibenzoylmethane). Further studies are proposed, such as formulating the compounds into emulsions or other common cosmetic presentations, as well as combining them with broadly-used UVB filters. We have also considered the need to establish its toxicological profile. © 2018 by the authors.
title Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters
title_short Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters
title_full Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters
title_fullStr Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters
title_full_unstemmed Absorption and photo-stability of substituted dibenzoylmethanes and chalcones as UVA filters
title_sort absorption and photo-stability of substituted dibenzoylmethanes and chalcones as uva filters
publishDate 2018
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20799284_v5_n2_p_Lazopulos
http://hdl.handle.net/20.500.12110/paper_20799284_v5_n2_p_Lazopulos
_version_ 1768542909322231808

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