Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics

Free standing hierarchical bioglass scaffolds were prepared by the ISISA (ice-segregation-induced self-assembly) method. Commercial low-cost precursors such as Ludox® HS-40 and cow milk were employed as the source of SiO2 and biominerals (Ca(ii), P(v), Na(i) and K(i)), respectively. Then, in a singl...

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Autores principales: Onna, Diego Ariel, Minaberry, Yanina Susana
Publicado: 2015
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20507518_v3_n15_p2971_Onna
http://hdl.handle.net/20.500.12110/paper_20507518_v3_n15_p2971_Onna
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spelling paper:paper_20507518_v3_n15_p2971_Onna2025-07-30T19:09:30Z Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics Onna, Diego Ariel Minaberry, Yanina Susana Biomineralization Porosity Scaffolds Self assembly Bioglass scaffolds Hierarchical porosity Ice segregation induced self assemblies Low-cost precursor Nanobuilding blocks Nanotemplates Simulated body fluids Templating effects Bioceramics Free standing hierarchical bioglass scaffolds were prepared by the ISISA (ice-segregation-induced self-assembly) method. Commercial low-cost precursors such as Ludox® HS-40 and cow milk were employed as the source of SiO2 and biominerals (Ca(ii), P(v), Na(i) and K(i)), respectively. Then, in a single macroscopic piece, three levels of porosity coexist due to the simultaneous templating effect of ice (macropores), milk (50-200 nm mesopores) and the voids left between preformed Ludox® nano building blocks (2-5 nm mesopores). These low cost and green biological nanotemplates, coupled with the ISISA texturing method, allows the preparation of free standing bioglass monoliths, with hierarchical porosity. The effect of the main preparative variables on the final texture is explored; in vitro biomineralization revealed a well-distributed hydroxyapatite-like nanoparticulated layer within 24 h of exposure to a simulated body fluid. This journal is © 2015 The Royal Society of Chemistry. Fil:Onna, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Minaberry, Y. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2015 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20507518_v3_n15_p2971_Onna http://hdl.handle.net/20.500.12110/paper_20507518_v3_n15_p2971_Onna
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Biomineralization
Porosity
Scaffolds
Self assembly
Bioglass scaffolds
Hierarchical porosity
Ice segregation induced self assemblies
Low-cost precursor
Nanobuilding blocks
Nanotemplates
Simulated body fluids
Templating effects
Bioceramics
spellingShingle Biomineralization
Porosity
Scaffolds
Self assembly
Bioglass scaffolds
Hierarchical porosity
Ice segregation induced self assemblies
Low-cost precursor
Nanobuilding blocks
Nanotemplates
Simulated body fluids
Templating effects
Bioceramics
Onna, Diego Ariel
Minaberry, Yanina Susana
Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics
topic_facet Biomineralization
Porosity
Scaffolds
Self assembly
Bioglass scaffolds
Hierarchical porosity
Ice segregation induced self assemblies
Low-cost precursor
Nanobuilding blocks
Nanotemplates
Simulated body fluids
Templating effects
Bioceramics
description Free standing hierarchical bioglass scaffolds were prepared by the ISISA (ice-segregation-induced self-assembly) method. Commercial low-cost precursors such as Ludox® HS-40 and cow milk were employed as the source of SiO2 and biominerals (Ca(ii), P(v), Na(i) and K(i)), respectively. Then, in a single macroscopic piece, three levels of porosity coexist due to the simultaneous templating effect of ice (macropores), milk (50-200 nm mesopores) and the voids left between preformed Ludox® nano building blocks (2-5 nm mesopores). These low cost and green biological nanotemplates, coupled with the ISISA texturing method, allows the preparation of free standing bioglass monoliths, with hierarchical porosity. The effect of the main preparative variables on the final texture is explored; in vitro biomineralization revealed a well-distributed hydroxyapatite-like nanoparticulated layer within 24 h of exposure to a simulated body fluid. This journal is © 2015 The Royal Society of Chemistry.
author Onna, Diego Ariel
Minaberry, Yanina Susana
author_facet Onna, Diego Ariel
Minaberry, Yanina Susana
author_sort Onna, Diego Ariel
title Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics
title_short Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics
title_full Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics
title_fullStr Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics
title_full_unstemmed Hierarchical bioglass scaffolds: Introducing the "milky way" for templated bioceramics
title_sort hierarchical bioglass scaffolds: introducing the "milky way" for templated bioceramics
publishDate 2015
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20507518_v3_n15_p2971_Onna
http://hdl.handle.net/20.500.12110/paper_20507518_v3_n15_p2971_Onna
work_keys_str_mv AT onnadiegoariel hierarchicalbioglassscaffoldsintroducingthemilkywayfortemplatedbioceramics
AT minaberryyaninasusana hierarchicalbioglassscaffoldsintroducingthemilkywayfortemplatedbioceramics
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