Cell entry of dengue virus
Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus...
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2008
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17460794_v3_n5_p471_Acosta http://hdl.handle.net/20.500.12110/paper_17460794_v3_n5_p471_Acosta |
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paper:paper_17460794_v3_n5_p471_Acosta2023-06-08T16:28:24Z Cell entry of dengue virus Antiviral therapy Dengue virus Envelope E glycoprotein Flavivirus Receptor Virus attachment Virus entry amantadine CD14 antigen chlorpromazine concanavalin A galactan glucan glucose regulated protein 78 glycoprotein E1 heat shock protein 70 heat shock protein 90 heparin laminin receptor lectin mannose receptor pentosan polysulfate pi 88 polyanion rimantadine suramin synthetic peptide tetracycline derivative tubulin virus receptor antiviral activity dengue Dengue virus host range human life cycle nonhuman priority journal protein function protein targeting review virion virus attachment virus entry virus replication Aedes aegypti Dengue virus Flavivirus Mammalia Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered. © 2008 Future Medicine Ltd. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17460794_v3_n5_p471_Acosta http://hdl.handle.net/20.500.12110/paper_17460794_v3_n5_p471_Acosta |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Antiviral therapy Dengue virus Envelope E glycoprotein Flavivirus Receptor Virus attachment Virus entry amantadine CD14 antigen chlorpromazine concanavalin A galactan glucan glucose regulated protein 78 glycoprotein E1 heat shock protein 70 heat shock protein 90 heparin laminin receptor lectin mannose receptor pentosan polysulfate pi 88 polyanion rimantadine suramin synthetic peptide tetracycline derivative tubulin virus receptor antiviral activity dengue Dengue virus host range human life cycle nonhuman priority journal protein function protein targeting review virion virus attachment virus entry virus replication Aedes aegypti Dengue virus Flavivirus Mammalia |
spellingShingle |
Antiviral therapy Dengue virus Envelope E glycoprotein Flavivirus Receptor Virus attachment Virus entry amantadine CD14 antigen chlorpromazine concanavalin A galactan glucan glucose regulated protein 78 glycoprotein E1 heat shock protein 70 heat shock protein 90 heparin laminin receptor lectin mannose receptor pentosan polysulfate pi 88 polyanion rimantadine suramin synthetic peptide tetracycline derivative tubulin virus receptor antiviral activity dengue Dengue virus host range human life cycle nonhuman priority journal protein function protein targeting review virion virus attachment virus entry virus replication Aedes aegypti Dengue virus Flavivirus Mammalia Cell entry of dengue virus |
topic_facet |
Antiviral therapy Dengue virus Envelope E glycoprotein Flavivirus Receptor Virus attachment Virus entry amantadine CD14 antigen chlorpromazine concanavalin A galactan glucan glucose regulated protein 78 glycoprotein E1 heat shock protein 70 heat shock protein 90 heparin laminin receptor lectin mannose receptor pentosan polysulfate pi 88 polyanion rimantadine suramin synthetic peptide tetracycline derivative tubulin virus receptor antiviral activity dengue Dengue virus host range human life cycle nonhuman priority journal protein function protein targeting review virion virus attachment virus entry virus replication Aedes aegypti Dengue virus Flavivirus Mammalia |
description |
Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered. © 2008 Future Medicine Ltd. |
title |
Cell entry of dengue virus |
title_short |
Cell entry of dengue virus |
title_full |
Cell entry of dengue virus |
title_fullStr |
Cell entry of dengue virus |
title_full_unstemmed |
Cell entry of dengue virus |
title_sort |
cell entry of dengue virus |
publishDate |
2008 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17460794_v3_n5_p471_Acosta http://hdl.handle.net/20.500.12110/paper_17460794_v3_n5_p471_Acosta |
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1768543533715685376 |