id paper:paper_17460794_v3_n5_p471_Acosta
record_format dspace
spelling paper:paper_17460794_v3_n5_p471_Acosta2023-06-08T16:28:24Z Cell entry of dengue virus Antiviral therapy Dengue virus Envelope E glycoprotein Flavivirus Receptor Virus attachment Virus entry amantadine CD14 antigen chlorpromazine concanavalin A galactan glucan glucose regulated protein 78 glycoprotein E1 heat shock protein 70 heat shock protein 90 heparin laminin receptor lectin mannose receptor pentosan polysulfate pi 88 polyanion rimantadine suramin synthetic peptide tetracycline derivative tubulin virus receptor antiviral activity dengue Dengue virus host range human life cycle nonhuman priority journal protein function protein targeting review virion virus attachment virus entry virus replication Aedes aegypti Dengue virus Flavivirus Mammalia Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered. © 2008 Future Medicine Ltd. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17460794_v3_n5_p471_Acosta http://hdl.handle.net/20.500.12110/paper_17460794_v3_n5_p471_Acosta
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Antiviral therapy
Dengue virus
Envelope E glycoprotein
Flavivirus
Receptor
Virus attachment
Virus entry
amantadine
CD14 antigen
chlorpromazine
concanavalin A
galactan
glucan
glucose regulated protein 78
glycoprotein E1
heat shock protein 70
heat shock protein 90
heparin
laminin receptor
lectin
mannose receptor
pentosan polysulfate
pi 88
polyanion
rimantadine
suramin
synthetic peptide
tetracycline derivative
tubulin
virus receptor
antiviral activity
dengue
Dengue virus
host range
human
life cycle
nonhuman
priority journal
protein function
protein targeting
review
virion
virus attachment
virus entry
virus replication
Aedes aegypti
Dengue virus
Flavivirus
Mammalia
spellingShingle Antiviral therapy
Dengue virus
Envelope E glycoprotein
Flavivirus
Receptor
Virus attachment
Virus entry
amantadine
CD14 antigen
chlorpromazine
concanavalin A
galactan
glucan
glucose regulated protein 78
glycoprotein E1
heat shock protein 70
heat shock protein 90
heparin
laminin receptor
lectin
mannose receptor
pentosan polysulfate
pi 88
polyanion
rimantadine
suramin
synthetic peptide
tetracycline derivative
tubulin
virus receptor
antiviral activity
dengue
Dengue virus
host range
human
life cycle
nonhuman
priority journal
protein function
protein targeting
review
virion
virus attachment
virus entry
virus replication
Aedes aegypti
Dengue virus
Flavivirus
Mammalia
Cell entry of dengue virus
topic_facet Antiviral therapy
Dengue virus
Envelope E glycoprotein
Flavivirus
Receptor
Virus attachment
Virus entry
amantadine
CD14 antigen
chlorpromazine
concanavalin A
galactan
glucan
glucose regulated protein 78
glycoprotein E1
heat shock protein 70
heat shock protein 90
heparin
laminin receptor
lectin
mannose receptor
pentosan polysulfate
pi 88
polyanion
rimantadine
suramin
synthetic peptide
tetracycline derivative
tubulin
virus receptor
antiviral activity
dengue
Dengue virus
host range
human
life cycle
nonhuman
priority journal
protein function
protein targeting
review
virion
virus attachment
virus entry
virus replication
Aedes aegypti
Dengue virus
Flavivirus
Mammalia
description Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered. © 2008 Future Medicine Ltd.
title Cell entry of dengue virus
title_short Cell entry of dengue virus
title_full Cell entry of dengue virus
title_fullStr Cell entry of dengue virus
title_full_unstemmed Cell entry of dengue virus
title_sort cell entry of dengue virus
publishDate 2008
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_17460794_v3_n5_p471_Acosta
http://hdl.handle.net/20.500.12110/paper_17460794_v3_n5_p471_Acosta
_version_ 1768543533715685376