Place conditioning in rats and ethanol

One of the most common procedures used to assess the hedonic value of a drug is the conditioned place (CP) which explores the preference or the aversion towards a previously drug paired context. In this paper we report on the different apparatus, procedures and dependant measures used on CP and the...

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Detalles Bibliográficos
Publicado: 2007
Materias:
Ethanol
Place conditioning
Rats
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15777057_v7_n3_p321_Kamenetzky
http://hdl.handle.net/20.500.12110/paper_15777057_v7_n3_p321_Kamenetzky
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_15777057_v7_n3_p321_Kamenetzky
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spelling paper:paper_15777057_v7_n3_p321_Kamenetzky2023-06-08T16:24:53Z Place conditioning in rats and ethanol Ethanol Place conditioning Rats One of the most common procedures used to assess the hedonic value of a drug is the conditioned place (CP) which explores the preference or the aversion towards a previously drug paired context. In this paper we report on the different apparatus, procedures and dependant measures used on CP and the main results found using ethanol. Finally we present a CP between-within subjects experiment on rats. The experiment consisted in three phases: (1) Pre-Test, we measured the animal's preference towards both contexts black place (BP) and white place (WP); (2) Conditioning, each animal received ethanol (dose: 0.5g/kg, i.p.) paired with the non preferred context and saline paired with the preferred context on alternate trials. A control group received vehicle in both contexts; (3) Post-Test same as pre-test. In both tests the time spent in each context was measured. The ethanol treated group reversed its place preference, whereas the saline group kept its initial preference. From this study we inferred that under this dose, ethanol has a positive hedonic value. © Intern. Jour. Psych. Psychol. Ther. 2007 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15777057_v7_n3_p321_Kamenetzky http://hdl.handle.net/20.500.12110/paper_15777057_v7_n3_p321_Kamenetzky
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Ethanol
Place conditioning
Rats
spellingShingle Ethanol
Place conditioning
Rats
Place conditioning in rats and ethanol
topic_facet Ethanol
Place conditioning
Rats
description One of the most common procedures used to assess the hedonic value of a drug is the conditioned place (CP) which explores the preference or the aversion towards a previously drug paired context. In this paper we report on the different apparatus, procedures and dependant measures used on CP and the main results found using ethanol. Finally we present a CP between-within subjects experiment on rats. The experiment consisted in three phases: (1) Pre-Test, we measured the animal's preference towards both contexts black place (BP) and white place (WP); (2) Conditioning, each animal received ethanol (dose: 0.5g/kg, i.p.) paired with the non preferred context and saline paired with the preferred context on alternate trials. A control group received vehicle in both contexts; (3) Post-Test same as pre-test. In both tests the time spent in each context was measured. The ethanol treated group reversed its place preference, whereas the saline group kept its initial preference. From this study we inferred that under this dose, ethanol has a positive hedonic value. © Intern. Jour. Psych. Psychol. Ther.
title Place conditioning in rats and ethanol
title_short Place conditioning in rats and ethanol
title_full Place conditioning in rats and ethanol
title_fullStr Place conditioning in rats and ethanol
title_full_unstemmed Place conditioning in rats and ethanol
title_sort place conditioning in rats and ethanol
publishDate 2007
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15777057_v7_n3_p321_Kamenetzky
http://hdl.handle.net/20.500.12110/paper_15777057_v7_n3_p321_Kamenetzky
_version_ 1768546692187029504

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