Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration
Introduction: Skin health and skin care to reduce the effects of aging are the main interests of many researchers. The skin is very important because it protects the body from various effects of the external environment, and studies of the largest organ of the human body have been conducted since an...
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2014
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15173151_v30_n1_p11_Teixeira http://hdl.handle.net/20.500.12110/paper_15173151_v30_n1_p11_Teixeira |
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paper:paper_15173151_v30_n1_p11_Teixeira2023-06-08T16:18:40Z Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration Confocal Raman spectroscopy Cosmetics NMF Skin aging Cosmetics Skin Biochemical composition Confocal Raman spectroscopy External environments NMF Noninvasive technique Skin aging Stratum corneum Superficial layers Hydration Introduction: Skin health and skin care to reduce the effects of aging are the main interests of many researchers. The skin is very important because it protects the body from various effects of the external environment, and studies of the largest organ of the human body have been conducted since antiquity. In skin, aging effects are severe enough to promote changes in cell structure and biochemical composition. In this study, we quantitatively analyzed the water content and natural moisturizing factor of human facial skin in vivo and in real time by confocal Raman spectroscopy. This non-invasive technique is capable of providing detailed information on the biochemical composition at different depth profiles in the skin. Methods: We studied 10 volunteers, phototype II (40 and 50 years old), using a confocal Raman system to examine the skin surface down to 25 μm. Raman spectra were obtained before product use (T0), and after 30 days of continuous use of cosmetics (T30). Results: The results show a significant increase of 6.4% in water content in the surface layer of the facial skin after the cosmetic use. The amounts of natural moisturizing factor (NMF) compounds were also increased. Urocanic acid underwent a greater change in relation to carboxylic acid pyrrolidone, with a 38.5% increase in the stratum corneum. Conclusion: Confocal Raman spectroscopy identified changes in the biochemical composition of the superficial layers of the epidermis, which suggests the anti-aging efficacy of the formulation. 2014 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15173151_v30_n1_p11_Teixeira http://hdl.handle.net/20.500.12110/paper_15173151_v30_n1_p11_Teixeira |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Confocal Raman spectroscopy Cosmetics NMF Skin aging Cosmetics Skin Biochemical composition Confocal Raman spectroscopy External environments NMF Noninvasive technique Skin aging Stratum corneum Superficial layers Hydration |
| spellingShingle |
Confocal Raman spectroscopy Cosmetics NMF Skin aging Cosmetics Skin Biochemical composition Confocal Raman spectroscopy External environments NMF Noninvasive technique Skin aging Stratum corneum Superficial layers Hydration Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration |
| topic_facet |
Confocal Raman spectroscopy Cosmetics NMF Skin aging Cosmetics Skin Biochemical composition Confocal Raman spectroscopy External environments NMF Noninvasive technique Skin aging Stratum corneum Superficial layers Hydration |
| description |
Introduction: Skin health and skin care to reduce the effects of aging are the main interests of many researchers. The skin is very important because it protects the body from various effects of the external environment, and studies of the largest organ of the human body have been conducted since antiquity. In skin, aging effects are severe enough to promote changes in cell structure and biochemical composition. In this study, we quantitatively analyzed the water content and natural moisturizing factor of human facial skin in vivo and in real time by confocal Raman spectroscopy. This non-invasive technique is capable of providing detailed information on the biochemical composition at different depth profiles in the skin. Methods: We studied 10 volunteers, phototype II (40 and 50 years old), using a confocal Raman system to examine the skin surface down to 25 μm. Raman spectra were obtained before product use (T0), and after 30 days of continuous use of cosmetics (T30). Results: The results show a significant increase of 6.4% in water content in the surface layer of the facial skin after the cosmetic use. The amounts of natural moisturizing factor (NMF) compounds were also increased. Urocanic acid underwent a greater change in relation to carboxylic acid pyrrolidone, with a 38.5% increase in the stratum corneum. Conclusion: Confocal Raman spectroscopy identified changes in the biochemical composition of the superficial layers of the epidermis, which suggests the anti-aging efficacy of the formulation. |
| title |
Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration |
| title_short |
Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration |
| title_full |
Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration |
| title_fullStr |
Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration |
| title_full_unstemmed |
Confocal raman spectroscopy: Determination of natural moisturizing factor profile related to skin hydration |
| title_sort |
confocal raman spectroscopy: determination of natural moisturizing factor profile related to skin hydration |
| publishDate |
2014 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15173151_v30_n1_p11_Teixeira http://hdl.handle.net/20.500.12110/paper_15173151_v30_n1_p11_Teixeira |
| _version_ |
1768546690703294464 |