Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T
In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(...
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2015
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13877003_v51_n_p110_Martinez http://hdl.handle.net/20.500.12110/paper_13877003_v51_n_p110_Martinez |
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paper:paper_13877003_v51_n_p110_Martinez |
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paper:paper_13877003_v51_n_p110_Martinez2023-06-08T16:13:00Z Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(DTPA)2-(R1 = 3.9 Mmol- 1•s-1). The results showed that the non-ion complex is a prospective MRI contrast agent. © 2014 Elsevier B.V. All rights reserved. 2015 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13877003_v51_n_p110_Martinez http://hdl.handle.net/20.500.12110/paper_13877003_v51_n_p110_Martinez |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity |
| spellingShingle |
Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T |
| topic_facet |
Contrast agent Gadolinium Macrocycle Magnetic resonance imaging Relaxivity |
| description |
In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1•s-1) was larger than that of Gd(DTPA)2-(R1 = 3.9 Mmol- 1•s-1). The results showed that the non-ion complex is a prospective MRI contrast agent. © 2014 Elsevier B.V. All rights reserved. |
| title |
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T |
| title_short |
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T |
| title_full |
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T |
| title_fullStr |
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T |
| title_full_unstemmed |
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. In vitro relaxivity studies at 0.2 T |
| title_sort |
synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. in vitro relaxivity studies at 0.2 t |
| publishDate |
2015 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13877003_v51_n_p110_Martinez http://hdl.handle.net/20.500.12110/paper_13877003_v51_n_p110_Martinez |
| _version_ |
1768544926500388864 |