Continuum theory of gene expression waves during vertebrate segmentation
The segmentation of the vertebrate body plan during embryonic development is a rhythmic and sequential process governed by genetic oscillations. These genetic oscillations give rise to traveling waves of gene expression in the segmenting tissue. Here we present a minimal continuum theory of vertebra...
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2015
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13672630_v17_n9_p_Jorg http://hdl.handle.net/20.500.12110/paper_13672630_v17_n9_p_Jorg |
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paper:paper_13672630_v17_n9_p_Jorg2023-06-08T16:12:08Z Continuum theory of gene expression waves during vertebrate segmentation coupled oscillators, morphogenesis, pattern formation Continuum mechanics Genes Tissue Continuum theory Dynamic patterns Embryonic development Function of time Pattern formation Segment lengths Sequential process Traveling wave Gene expression The segmentation of the vertebrate body plan during embryonic development is a rhythmic and sequential process governed by genetic oscillations. These genetic oscillations give rise to traveling waves of gene expression in the segmenting tissue. Here we present a minimal continuum theory of vertebrate segmentation that captures the key principles governing the dynamic patterns of gene expression including the effects of shortening of the oscillating tissue. We show that our theory can quantitatively account for the key features of segmentation observed in zebrafish, in particular the shape of the wave patterns, the period of segmentation and the segment length as a function of time. © 2015 IOP Publishing Ltd and Deutsche Physikalische Gesellschaft. 2015 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13672630_v17_n9_p_Jorg http://hdl.handle.net/20.500.12110/paper_13672630_v17_n9_p_Jorg |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
coupled oscillators, morphogenesis, pattern formation Continuum mechanics Genes Tissue Continuum theory Dynamic patterns Embryonic development Function of time Pattern formation Segment lengths Sequential process Traveling wave Gene expression |
| spellingShingle |
coupled oscillators, morphogenesis, pattern formation Continuum mechanics Genes Tissue Continuum theory Dynamic patterns Embryonic development Function of time Pattern formation Segment lengths Sequential process Traveling wave Gene expression Continuum theory of gene expression waves during vertebrate segmentation |
| topic_facet |
coupled oscillators, morphogenesis, pattern formation Continuum mechanics Genes Tissue Continuum theory Dynamic patterns Embryonic development Function of time Pattern formation Segment lengths Sequential process Traveling wave Gene expression |
| description |
The segmentation of the vertebrate body plan during embryonic development is a rhythmic and sequential process governed by genetic oscillations. These genetic oscillations give rise to traveling waves of gene expression in the segmenting tissue. Here we present a minimal continuum theory of vertebrate segmentation that captures the key principles governing the dynamic patterns of gene expression including the effects of shortening of the oscillating tissue. We show that our theory can quantitatively account for the key features of segmentation observed in zebrafish, in particular the shape of the wave patterns, the period of segmentation and the segment length as a function of time. © 2015 IOP Publishing Ltd and Deutsche Physikalische Gesellschaft. |
| title |
Continuum theory of gene expression waves during vertebrate segmentation |
| title_short |
Continuum theory of gene expression waves during vertebrate segmentation |
| title_full |
Continuum theory of gene expression waves during vertebrate segmentation |
| title_fullStr |
Continuum theory of gene expression waves during vertebrate segmentation |
| title_full_unstemmed |
Continuum theory of gene expression waves during vertebrate segmentation |
| title_sort |
continuum theory of gene expression waves during vertebrate segmentation |
| publishDate |
2015 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13672630_v17_n9_p_Jorg http://hdl.handle.net/20.500.12110/paper_13672630_v17_n9_p_Jorg |
| _version_ |
1768545892411899904 |