Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders

This study involved 50 human immunodeficiency virus (HIV)-positive patients in various stages of the disease to identify signs and symptoms suggestive of rheumatologic disorders and to determine how frequently such findings mimic rheumatologic pictures. Control subjects were 25 ambulatory HIV-negati...

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Publicado: 1996
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v2_n3_p125_Rosemffet
http://hdl.handle.net/20.500.12110/paper_10761608_v2_n3_p125_Rosemffet
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spelling paper:paper_10761608_v2_n3_p125_Rosemffet2023-06-08T16:05:21Z Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders Human immunodeficiency virus Mimicry Reiter's syndrome Rheumatic disorders adolescent adult arthralgia arthritis article clinical article clinical examination controlled study female human Human immunodeficiency virus infection lymphocyte count male myalgia priority journal rheumatology This study involved 50 human immunodeficiency virus (HIV)-positive patients in various stages of the disease to identify signs and symptoms suggestive of rheumatologic disorders and to determine how frequently such findings mimic rheumatologic pictures. Control subjects were 25 ambulatory HIV-negative patients with similar risk factors, mostly drug abuse. Although arthralgias and myalgias were reported in both groups, arthritis was only detected in the HIV-positive group. Twenty-four HIV cases presented two or more signs or symptoms suggestive of rheumatic disorders versus only six non- HIV cases (p < 0.04). Some features were suggestive of systemic lupus erythematosus, vasculitis-panarteritis nodosa, Sjogren's syndrome, Behcet's syndrome and rheumatoid arthritis, although no patients met criteria for these diseases. Reiter's syndrome was diagnosed in two (4%) HIV-positive patients. On correlating CD4 lymphocyte levels and rheumatic symptomatology, the more severely immunocompromised cases were found to present musculoskeletal manifestations with greater frequency. Potential HIV infection should be considered in differential diagnosis of questionable cases of rheumatic disease to avoid both misdiagnosis and the institution of therapies liable to worsen the immunodeficiency syndrome. 1996 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v2_n3_p125_Rosemffet http://hdl.handle.net/20.500.12110/paper_10761608_v2_n3_p125_Rosemffet
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Human immunodeficiency virus
Mimicry
Reiter's syndrome
Rheumatic disorders
adolescent
adult
arthralgia
arthritis
article
clinical article
clinical examination
controlled study
female
human
Human immunodeficiency virus infection
lymphocyte count
male
myalgia
priority journal
rheumatology
spellingShingle Human immunodeficiency virus
Mimicry
Reiter's syndrome
Rheumatic disorders
adolescent
adult
arthralgia
arthritis
article
clinical article
clinical examination
controlled study
female
human
Human immunodeficiency virus infection
lymphocyte count
male
myalgia
priority journal
rheumatology
Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders
topic_facet Human immunodeficiency virus
Mimicry
Reiter's syndrome
Rheumatic disorders
adolescent
adult
arthralgia
arthritis
article
clinical article
clinical examination
controlled study
female
human
Human immunodeficiency virus infection
lymphocyte count
male
myalgia
priority journal
rheumatology
description This study involved 50 human immunodeficiency virus (HIV)-positive patients in various stages of the disease to identify signs and symptoms suggestive of rheumatologic disorders and to determine how frequently such findings mimic rheumatologic pictures. Control subjects were 25 ambulatory HIV-negative patients with similar risk factors, mostly drug abuse. Although arthralgias and myalgias were reported in both groups, arthritis was only detected in the HIV-positive group. Twenty-four HIV cases presented two or more signs or symptoms suggestive of rheumatic disorders versus only six non- HIV cases (p < 0.04). Some features were suggestive of systemic lupus erythematosus, vasculitis-panarteritis nodosa, Sjogren's syndrome, Behcet's syndrome and rheumatoid arthritis, although no patients met criteria for these diseases. Reiter's syndrome was diagnosed in two (4%) HIV-positive patients. On correlating CD4 lymphocyte levels and rheumatic symptomatology, the more severely immunocompromised cases were found to present musculoskeletal manifestations with greater frequency. Potential HIV infection should be considered in differential diagnosis of questionable cases of rheumatic disease to avoid both misdiagnosis and the institution of therapies liable to worsen the immunodeficiency syndrome.
title Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders
title_short Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders
title_full Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders
title_fullStr Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders
title_full_unstemmed Human immunodeficiency virus infection: Search for musculoskeletal manifestations and mimicking of rheumatologic disorders
title_sort human immunodeficiency virus infection: search for musculoskeletal manifestations and mimicking of rheumatologic disorders
publishDate 1996
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v2_n3_p125_Rosemffet
http://hdl.handle.net/20.500.12110/paper_10761608_v2_n3_p125_Rosemffet
_version_ 1768545295244722176