Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus
An opaque screen moving overhead elicits an escape response in the crab Chasmagnathus that after a few presentations habituates for a long period (long-term habituation, LTH). Previous results suggested that spaced (15 trials separated by 171 s) and massed training (300 trials without rest interval)...
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1999
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10747427_v71_n1_p34_Hermitte http://hdl.handle.net/20.500.12110/paper_10747427_v71_n1_p34_Hermitte |
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paper:paper_10747427_v71_n1_p34_Hermitte2023-06-08T16:05:05Z Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus Hermitte, Gabriela Pedreira, Maria Eugenia Tomsic, Daniel Crustacea Cycloheximide Habituation Learning Massed and spaced training Protein synthesis cycloheximide animal experiment article conditioning controlled study crab drug effect habituation learning long term memory male memory consolidation nonhuman protein synthesis training An opaque screen moving overhead elicits an escape response in the crab Chasmagnathus that after a few presentations habituates for a long period (long-term habituation, LTH). Previous results suggested that spaced (15 trials separated by 171 s) and massed training (300 trials without rest interval) were correlated with two different memory components of LTH. The present experiments were aimed at further studying the mechanisms subserving these components. Results indicate that LTH acquired by spaced but not by massed training is blocked either by a training-to-testing context shift or by cycloheximide (15-25 μg) pre- or posttraining injection and that LTH after spaced training persists for longer time (5 days) than after massed training (2 days). A model based on these results that distinguishes two LTH- memory components is proposed: a (context-signal) LTH yielded by spaced training, dependent of context, sensitive to cycloheximide (CYX), and long lasting; and a (signal) LTH yielded by massed training, dependent only on the signal invariance, insensitive to CYX, and shorter lasting. Fil:Hermitte, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pedreira, M.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Tomsic, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1999 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10747427_v71_n1_p34_Hermitte http://hdl.handle.net/20.500.12110/paper_10747427_v71_n1_p34_Hermitte |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Crustacea Cycloheximide Habituation Learning Massed and spaced training Protein synthesis cycloheximide animal experiment article conditioning controlled study crab drug effect habituation learning long term memory male memory consolidation nonhuman protein synthesis training |
| spellingShingle |
Crustacea Cycloheximide Habituation Learning Massed and spaced training Protein synthesis cycloheximide animal experiment article conditioning controlled study crab drug effect habituation learning long term memory male memory consolidation nonhuman protein synthesis training Hermitte, Gabriela Pedreira, Maria Eugenia Tomsic, Daniel Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus |
| topic_facet |
Crustacea Cycloheximide Habituation Learning Massed and spaced training Protein synthesis cycloheximide animal experiment article conditioning controlled study crab drug effect habituation learning long term memory male memory consolidation nonhuman protein synthesis training |
| description |
An opaque screen moving overhead elicits an escape response in the crab Chasmagnathus that after a few presentations habituates for a long period (long-term habituation, LTH). Previous results suggested that spaced (15 trials separated by 171 s) and massed training (300 trials without rest interval) were correlated with two different memory components of LTH. The present experiments were aimed at further studying the mechanisms subserving these components. Results indicate that LTH acquired by spaced but not by massed training is blocked either by a training-to-testing context shift or by cycloheximide (15-25 μg) pre- or posttraining injection and that LTH after spaced training persists for longer time (5 days) than after massed training (2 days). A model based on these results that distinguishes two LTH- memory components is proposed: a (context-signal) LTH yielded by spaced training, dependent of context, sensitive to cycloheximide (CYX), and long lasting; and a (signal) LTH yielded by massed training, dependent only on the signal invariance, insensitive to CYX, and shorter lasting. |
| author |
Hermitte, Gabriela Pedreira, Maria Eugenia Tomsic, Daniel |
| author_facet |
Hermitte, Gabriela Pedreira, Maria Eugenia Tomsic, Daniel |
| author_sort |
Hermitte, Gabriela |
| title |
Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus |
| title_short |
Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus |
| title_full |
Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus |
| title_fullStr |
Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus |
| title_full_unstemmed |
Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus |
| title_sort |
context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab chasmagnathus |
| publishDate |
1999 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10747427_v71_n1_p34_Hermitte http://hdl.handle.net/20.500.12110/paper_10747427_v71_n1_p34_Hermitte |
| work_keys_str_mv |
AT hermittegabriela contextshiftandproteinsynthesisinhibitiondisruptlongtermhabituationafterspacedbutnotmassedtraininginthecrabchasmagnathus AT pedreiramariaeugenia contextshiftandproteinsynthesisinhibitiondisruptlongtermhabituationafterspacedbutnotmassedtraininginthecrabchasmagnathus AT tomsicdaniel contextshiftandproteinsynthesisinhibitiondisruptlongtermhabituationafterspacedbutnotmassedtraininginthecrabchasmagnathus |
| _version_ |
1768545155193765888 |