2-C-Methyluridine modified hammerhead ribozyme against the estrogen receptor
A new synthesis of 2′-C-methyluridine phosphoramidite is presented. Special emphasis is dedicated to the improvement of the protection of the tertiary 2′-hydroxyl group. Comparison to previous protecting strategies and analysis of stability under 5′-DMTr removing conditions are discussed. The synthe...
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2010
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0960894X_v20_n9_p2806_Pontiggia http://hdl.handle.net/20.500.12110/paper_0960894X_v20_n9_p2806_Pontiggia |
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