Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers
Orthostatic intolerance is occasionally reported by patients with syringomyelia and is usually attributed to vestibular symptoms or neurogenic orthostatic hypotension. Postural tachycardia syndrome has not been previously described in syringomyelia. A patient with long-standing syringomyelia and a C...
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2001
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09599851_v11_n4_p265_Nogues http://hdl.handle.net/20.500.12110/paper_09599851_v11_n4_p265_Nogues |
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paper:paper_09599851_v11_n4_p265_Nogues2025-07-30T18:33:26Z Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers Autonomic dysfunction Postural tachycardia syndrome (POTS) Syncope Syringomyelia atenolol benzodiazepine derivative beta adrenergic receptor blocking agent chlorpromazine domperidone fludrocortisone adult Arnold Chiari malformation article autonomic denervation body posture brain decompression case report clinical feature disease association drug response female head tilting human nuclear magnetic resonance imaging orthostatic hypotension panic posterior fossa postural tachycardia syndrome shunting standing syncope syringomyelia tachycardia Adrenergic beta-Antagonists Anti-Inflammatory Agents Autonomic Nervous System Female Fludrocortisone Humans Magnetic Resonance Imaging Middle Aged Posture Syringomyelia Tachycardia Orthostatic intolerance is occasionally reported by patients with syringomyelia and is usually attributed to vestibular symptoms or neurogenic orthostatic hypotension. Postural tachycardia syndrome has not been previously described in syringomyelia. A patient with long-standing syringomyelia and a Chiari type I anomaly developed disabling "panic-like" attacks associated to orthostatic intolerance five years after posterior fossa decompression and shunting of the syrinx. A head-up tilt test showed an early phase of postural orthostatic tachycardia followed by progressive arterial hypotension and bradycardia as seen in neurally mediated syncope. A magnetic resonance imaging scan showed a collapsed syrinx from the 3rd cervical to the 12th thoracic vertebra without syringobulbia. Fludrocortisone and β-blockers led to resolution of symptoms. Partial sympathetic denervation of the legs in syringomyelia might explain the occasional occurrence of postural tachycardia syndrome. Postural tachycardia syndrome may be included as a possible cause of orthostatic symptoms in syringomyelia patients. 2001 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09599851_v11_n4_p265_Nogues http://hdl.handle.net/20.500.12110/paper_09599851_v11_n4_p265_Nogues |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Autonomic dysfunction Postural tachycardia syndrome (POTS) Syncope Syringomyelia atenolol benzodiazepine derivative beta adrenergic receptor blocking agent chlorpromazine domperidone fludrocortisone adult Arnold Chiari malformation article autonomic denervation body posture brain decompression case report clinical feature disease association drug response female head tilting human nuclear magnetic resonance imaging orthostatic hypotension panic posterior fossa postural tachycardia syndrome shunting standing syncope syringomyelia tachycardia Adrenergic beta-Antagonists Anti-Inflammatory Agents Autonomic Nervous System Female Fludrocortisone Humans Magnetic Resonance Imaging Middle Aged Posture Syringomyelia Tachycardia |
| spellingShingle |
Autonomic dysfunction Postural tachycardia syndrome (POTS) Syncope Syringomyelia atenolol benzodiazepine derivative beta adrenergic receptor blocking agent chlorpromazine domperidone fludrocortisone adult Arnold Chiari malformation article autonomic denervation body posture brain decompression case report clinical feature disease association drug response female head tilting human nuclear magnetic resonance imaging orthostatic hypotension panic posterior fossa postural tachycardia syndrome shunting standing syncope syringomyelia tachycardia Adrenergic beta-Antagonists Anti-Inflammatory Agents Autonomic Nervous System Female Fludrocortisone Humans Magnetic Resonance Imaging Middle Aged Posture Syringomyelia Tachycardia Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers |
| topic_facet |
Autonomic dysfunction Postural tachycardia syndrome (POTS) Syncope Syringomyelia atenolol benzodiazepine derivative beta adrenergic receptor blocking agent chlorpromazine domperidone fludrocortisone adult Arnold Chiari malformation article autonomic denervation body posture brain decompression case report clinical feature disease association drug response female head tilting human nuclear magnetic resonance imaging orthostatic hypotension panic posterior fossa postural tachycardia syndrome shunting standing syncope syringomyelia tachycardia Adrenergic beta-Antagonists Anti-Inflammatory Agents Autonomic Nervous System Female Fludrocortisone Humans Magnetic Resonance Imaging Middle Aged Posture Syringomyelia Tachycardia |
| description |
Orthostatic intolerance is occasionally reported by patients with syringomyelia and is usually attributed to vestibular symptoms or neurogenic orthostatic hypotension. Postural tachycardia syndrome has not been previously described in syringomyelia. A patient with long-standing syringomyelia and a Chiari type I anomaly developed disabling "panic-like" attacks associated to orthostatic intolerance five years after posterior fossa decompression and shunting of the syrinx. A head-up tilt test showed an early phase of postural orthostatic tachycardia followed by progressive arterial hypotension and bradycardia as seen in neurally mediated syncope. A magnetic resonance imaging scan showed a collapsed syrinx from the 3rd cervical to the 12th thoracic vertebra without syringobulbia. Fludrocortisone and β-blockers led to resolution of symptoms. Partial sympathetic denervation of the legs in syringomyelia might explain the occasional occurrence of postural tachycardia syndrome. Postural tachycardia syndrome may be included as a possible cause of orthostatic symptoms in syringomyelia patients. |
| title |
Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers |
| title_short |
Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers |
| title_full |
Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers |
| title_fullStr |
Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers |
| title_full_unstemmed |
Postural tachycardia syndrome in syringomyelia: Response to fludrocortisone and β-blockers |
| title_sort |
postural tachycardia syndrome in syringomyelia: response to fludrocortisone and β-blockers |
| publishDate |
2001 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09599851_v11_n4_p265_Nogues http://hdl.handle.net/20.500.12110/paper_09599851_v11_n4_p265_Nogues |
| _version_ |
1840323475879755776 |