Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain
3a-Acetoxy-5β-cholan-24-oic acid was transformed into 3β-acetoxy-5β-pregnan-20-one by a sequence of reactions that involves inversion of the configuration at C-3 and degradation of the side chain of the bile acid. The procedure would allow the introduction of a label at C-21 of the final compound. ©...
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1984
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09320776_v39_n11_p1617_Deluca http://hdl.handle.net/20.500.12110/paper_09320776_v39_n11_p1617_Deluca |
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paper:paper_09320776_v39_n11_p1617_Deluca |
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paper:paper_09320776_v39_n11_p1617_Deluca2023-06-08T15:53:04Z Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain Deluca, Mónica Eva Seldes, Alicia Marta Garraffo, Hugo Martín Gros, Eduardo Gervasio 3beta acetoxy 5beta pregnan 20 one drug analysis drug identification drug structure drug synthesis infrared spectrometry mass spectrometry methodology nonhuman nuclear magnetic resonance proton nuclear magnetic resonance theoretical study 3a-Acetoxy-5β-cholan-24-oic acid was transformed into 3β-acetoxy-5β-pregnan-20-one by a sequence of reactions that involves inversion of the configuration at C-3 and degradation of the side chain of the bile acid. The procedure would allow the introduction of a label at C-21 of the final compound. © 1984, Walter de Gruyter. All rights reserved. Fil:Deluca, M.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Garraffo, H.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1984 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09320776_v39_n11_p1617_Deluca http://hdl.handle.net/20.500.12110/paper_09320776_v39_n11_p1617_Deluca |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
3beta acetoxy 5beta pregnan 20 one drug analysis drug identification drug structure drug synthesis infrared spectrometry mass spectrometry methodology nonhuman nuclear magnetic resonance proton nuclear magnetic resonance theoretical study |
| spellingShingle |
3beta acetoxy 5beta pregnan 20 one drug analysis drug identification drug structure drug synthesis infrared spectrometry mass spectrometry methodology nonhuman nuclear magnetic resonance proton nuclear magnetic resonance theoretical study Deluca, Mónica Eva Seldes, Alicia Marta Garraffo, Hugo Martín Gros, Eduardo Gervasio Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain |
| topic_facet |
3beta acetoxy 5beta pregnan 20 one drug analysis drug identification drug structure drug synthesis infrared spectrometry mass spectrometry methodology nonhuman nuclear magnetic resonance proton nuclear magnetic resonance theoretical study |
| description |
3a-Acetoxy-5β-cholan-24-oic acid was transformed into 3β-acetoxy-5β-pregnan-20-one by a sequence of reactions that involves inversion of the configuration at C-3 and degradation of the side chain of the bile acid. The procedure would allow the introduction of a label at C-21 of the final compound. © 1984, Walter de Gruyter. All rights reserved. |
| author |
Deluca, Mónica Eva Seldes, Alicia Marta Garraffo, Hugo Martín Gros, Eduardo Gervasio |
| author_facet |
Deluca, Mónica Eva Seldes, Alicia Marta Garraffo, Hugo Martín Gros, Eduardo Gervasio |
| author_sort |
Deluca, Mónica Eva |
| title |
Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain |
| title_short |
Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain |
| title_full |
Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain |
| title_fullStr |
Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain |
| title_full_unstemmed |
Preparation of 3β -Acetoxy-5β-pregnan-20-one from 3 a- Acetoxy-5β-cholan-24-oic Acid Aimed at the Isotopic Labelling of the Pregnane Side Chain |
| title_sort |
preparation of 3β -acetoxy-5β-pregnan-20-one from 3 a- acetoxy-5β-cholan-24-oic acid aimed at the isotopic labelling of the pregnane side chain |
| publishDate |
1984 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09320776_v39_n11_p1617_Deluca http://hdl.handle.net/20.500.12110/paper_09320776_v39_n11_p1617_Deluca |
| work_keys_str_mv |
AT delucamonicaeva preparationof3bacetoxy5bpregnan20onefrom3aacetoxy5bcholan24oicacidaimedattheisotopiclabellingofthepregnanesidechain AT seldesaliciamarta preparationof3bacetoxy5bpregnan20onefrom3aacetoxy5bcholan24oicacidaimedattheisotopiclabellingofthepregnanesidechain AT garraffohugomartin preparationof3bacetoxy5bpregnan20onefrom3aacetoxy5bcholan24oicacidaimedattheisotopiclabellingofthepregnanesidechain AT groseduardogervasio preparationof3bacetoxy5bpregnan20onefrom3aacetoxy5bcholan24oicacidaimedattheisotopiclabellingofthepregnanesidechain |
| _version_ |
1768545014653124608 |