Urease functionalized silica: A biohybrid substrate to drive self-mineralization

A study was conducted to demonstrate the use of urease to drive HAP-like film deposition over the silica surface under mild conditions. The study used a synthetic monodispersed submicrometric silica spheres as a model substrate to simplify mass transport boundary conditions. Direct adsorption of ure...

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Detalles Bibliográficos
Autor principal:	Jobbagy, Matias
Publicado:	2008
Materias:	Adsorption Aldehydes Amines Coupling agents Hazardous materials Mineralogy Polymers Covalent attachments Enzyme loadings Film depositions Functionalization Functionalized silicas Glutaraldehyde Mass transports Model substrates Mono-dispersed Nucleation and growths Silica particles Silica spheres Silica surfaces Silica
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_08974756_v20_n24_p7368_Ortega http://hdl.handle.net/20.500.12110/paper_08974756_v20_n24_p7368_Ortega
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_08974756_v20_n24_p7368_Ortega
record_format	dspace
spelling	paper:paper_08974756_v20_n24_p7368_Ortega2023-06-08T15:49:17Z Urease functionalized silica: A biohybrid substrate to drive self-mineralization Jobbagy, Matias Adsorption Aldehydes Amines Coupling agents Hazardous materials Mineralogy Polymers Covalent attachments Enzyme loadings Film depositions Functionalization Functionalized silicas Glutaraldehyde Mass transports Model substrates Mono-dispersed Nucleation and growths Silica particles Silica spheres Silica surfaces Silica A study was conducted to demonstrate the use of urease to drive HAP-like film deposition over the silica surface under mild conditions. The study used a synthetic monodispersed submicrometric silica spheres as a model substrate to simplify mass transport boundary conditions. Direct adsorption of urease on the silica surface was carried out to achieve silica functionalization. Covalent anchorage was also used to perform proper active enzyme loadings on the silica surface without shielding it with polyelectrolytes. Amino-capped silica particles were synthesized and biofunctionalized with urease during the study using direct covalent attachment with glutaraldehyde as coupling agent. This method proved that urease functionalized silica can be used as an interface for nucleation and growth of HAP-like coatings under mild conditions and short aging times. Fil:Jobbágy, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_08974756_v20_n24_p7368_Ortega http://hdl.handle.net/20.500.12110/paper_08974756_v20_n24_p7368_Ortega
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Adsorption Aldehydes Amines Coupling agents Hazardous materials Mineralogy Polymers Covalent attachments Enzyme loadings Film depositions Functionalization Functionalized silicas Glutaraldehyde Mass transports Model substrates Mono-dispersed Nucleation and growths Silica particles Silica spheres Silica surfaces Silica
spellingShingle	Adsorption Aldehydes Amines Coupling agents Hazardous materials Mineralogy Polymers Covalent attachments Enzyme loadings Film depositions Functionalization Functionalized silicas Glutaraldehyde Mass transports Model substrates Mono-dispersed Nucleation and growths Silica particles Silica spheres Silica surfaces Silica Jobbagy, Matias Urease functionalized silica: A biohybrid substrate to drive self-mineralization
topic_facet	Adsorption Aldehydes Amines Coupling agents Hazardous materials Mineralogy Polymers Covalent attachments Enzyme loadings Film depositions Functionalization Functionalized silicas Glutaraldehyde Mass transports Model substrates Mono-dispersed Nucleation and growths Silica particles Silica spheres Silica surfaces Silica
description	A study was conducted to demonstrate the use of urease to drive HAP-like film deposition over the silica surface under mild conditions. The study used a synthetic monodispersed submicrometric silica spheres as a model substrate to simplify mass transport boundary conditions. Direct adsorption of urease on the silica surface was carried out to achieve silica functionalization. Covalent anchorage was also used to perform proper active enzyme loadings on the silica surface without shielding it with polyelectrolytes. Amino-capped silica particles were synthesized and biofunctionalized with urease during the study using direct covalent attachment with glutaraldehyde as coupling agent. This method proved that urease functionalized silica can be used as an interface for nucleation and growth of HAP-like coatings under mild conditions and short aging times.
author	Jobbagy, Matias
author_facet	Jobbagy, Matias
author_sort	Jobbagy, Matias
title	Urease functionalized silica: A biohybrid substrate to drive self-mineralization
title_short	Urease functionalized silica: A biohybrid substrate to drive self-mineralization
title_full	Urease functionalized silica: A biohybrid substrate to drive self-mineralization
title_fullStr	Urease functionalized silica: A biohybrid substrate to drive self-mineralization
title_full_unstemmed	Urease functionalized silica: A biohybrid substrate to drive self-mineralization
title_sort	urease functionalized silica: a biohybrid substrate to drive self-mineralization
publishDate	2008
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_08974756_v20_n24_p7368_Ortega http://hdl.handle.net/20.500.12110/paper_08974756_v20_n24_p7368_Ortega
work_keys_str_mv	AT jobbagymatias ureasefunctionalizedsilicaabiohybridsubstratetodriveselfmineralization
_version_	1768543378386976768

Urease functionalized silica: A biohybrid substrate to drive self-mineralization

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