Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts
The effects of Cedrela lilloi and Trichilia elegans (Meliaceae) aqueous leaf extracts on several parameters of the mouse immune system were studied. Both extracts showed a strong anticomplementary activity and inhibited the phagocytosis of opsonized sheep erythrocytes and the activation of the oxida...
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1997
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03788741_v55_n2_p99_Nores http://hdl.handle.net/20.500.12110/paper_03788741_v55_n2_p99_Nores |
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paper:paper_03788741_v55_n2_p99_Nores2023-06-08T15:40:33Z Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts Courréges, María Cecilia Benencia, Fabián Coulombié, Félix Carlos Cedrela lilloi Immune system Immunomodulation Leaf extracts Mouse Trichilia elegans plant extract zymosan aerobic metabolism animal cell animal experiment animal model Argentina article complement inhibition controlled study delayed hypersensitivity female immunomodulation lymphocyte culture lymphocyte proliferation medicinal plant mouse nonhuman peritoneum macrophage phagocytosis plant leaf sheep erythrocyte spleen lymphocyte subcutaneous drug administration T lymphocyte traditional medicine Adjuvants, Immunologic Animals Argentina Cell Separation Complement Activation Erythrocytes Female Hypersensitivity, Delayed Lymphocyte Activation Macrophages, Peritoneal Mice Mice, Inbred BALB C Nitroblue Tetrazolium Phagocytosis Plant Extracts Plant Leaves Sheep T-Lymphocytes Zymosan The effects of Cedrela lilloi and Trichilia elegans (Meliaceae) aqueous leaf extracts on several parameters of the mouse immune system were studied. Both extracts showed a strong anticomplementary activity and inhibited the phagocytosis of opsonized sheep erythrocytes and the activation of the oxidative metabolism by opsonized zymosan on peritoneal macrophages. The in vitro proliferation of spleen T-lymphocytes was also impaired. Furthermore, treatment of mice with the extracts diminished the delayed-type hypersensitivity response to sheep erythrocytes. These results suggest that both extracts exert a marked immunomodulatory effect on the mouse immune system. Fil:Courrèges, M.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Benencia, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Coulombié, F.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03788741_v55_n2_p99_Nores http://hdl.handle.net/20.500.12110/paper_03788741_v55_n2_p99_Nores |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Cedrela lilloi Immune system Immunomodulation Leaf extracts Mouse Trichilia elegans plant extract zymosan aerobic metabolism animal cell animal experiment animal model Argentina article complement inhibition controlled study delayed hypersensitivity female immunomodulation lymphocyte culture lymphocyte proliferation medicinal plant mouse nonhuman peritoneum macrophage phagocytosis plant leaf sheep erythrocyte spleen lymphocyte subcutaneous drug administration T lymphocyte traditional medicine Adjuvants, Immunologic Animals Argentina Cell Separation Complement Activation Erythrocytes Female Hypersensitivity, Delayed Lymphocyte Activation Macrophages, Peritoneal Mice Mice, Inbred BALB C Nitroblue Tetrazolium Phagocytosis Plant Extracts Plant Leaves Sheep T-Lymphocytes Zymosan |
| spellingShingle |
Cedrela lilloi Immune system Immunomodulation Leaf extracts Mouse Trichilia elegans plant extract zymosan aerobic metabolism animal cell animal experiment animal model Argentina article complement inhibition controlled study delayed hypersensitivity female immunomodulation lymphocyte culture lymphocyte proliferation medicinal plant mouse nonhuman peritoneum macrophage phagocytosis plant leaf sheep erythrocyte spleen lymphocyte subcutaneous drug administration T lymphocyte traditional medicine Adjuvants, Immunologic Animals Argentina Cell Separation Complement Activation Erythrocytes Female Hypersensitivity, Delayed Lymphocyte Activation Macrophages, Peritoneal Mice Mice, Inbred BALB C Nitroblue Tetrazolium Phagocytosis Plant Extracts Plant Leaves Sheep T-Lymphocytes Zymosan Courréges, María Cecilia Benencia, Fabián Coulombié, Félix Carlos Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts |
| topic_facet |
Cedrela lilloi Immune system Immunomodulation Leaf extracts Mouse Trichilia elegans plant extract zymosan aerobic metabolism animal cell animal experiment animal model Argentina article complement inhibition controlled study delayed hypersensitivity female immunomodulation lymphocyte culture lymphocyte proliferation medicinal plant mouse nonhuman peritoneum macrophage phagocytosis plant leaf sheep erythrocyte spleen lymphocyte subcutaneous drug administration T lymphocyte traditional medicine Adjuvants, Immunologic Animals Argentina Cell Separation Complement Activation Erythrocytes Female Hypersensitivity, Delayed Lymphocyte Activation Macrophages, Peritoneal Mice Mice, Inbred BALB C Nitroblue Tetrazolium Phagocytosis Plant Extracts Plant Leaves Sheep T-Lymphocytes Zymosan |
| description |
The effects of Cedrela lilloi and Trichilia elegans (Meliaceae) aqueous leaf extracts on several parameters of the mouse immune system were studied. Both extracts showed a strong anticomplementary activity and inhibited the phagocytosis of opsonized sheep erythrocytes and the activation of the oxidative metabolism by opsonized zymosan on peritoneal macrophages. The in vitro proliferation of spleen T-lymphocytes was also impaired. Furthermore, treatment of mice with the extracts diminished the delayed-type hypersensitivity response to sheep erythrocytes. These results suggest that both extracts exert a marked immunomodulatory effect on the mouse immune system. |
| author |
Courréges, María Cecilia Benencia, Fabián Coulombié, Félix Carlos |
| author_facet |
Courréges, María Cecilia Benencia, Fabián Coulombié, Félix Carlos |
| author_sort |
Courréges, María Cecilia |
| title |
Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts |
| title_short |
Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts |
| title_full |
Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts |
| title_fullStr |
Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts |
| title_full_unstemmed |
Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts |
| title_sort |
immunomodulatory activities of cedrela lilloi and trichilia elegans aqueous leaf extracts |
| publishDate |
1997 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03788741_v55_n2_p99_Nores http://hdl.handle.net/20.500.12110/paper_03788741_v55_n2_p99_Nores |
| work_keys_str_mv |
AT courregesmariacecilia immunomodulatoryactivitiesofcedrelalilloiandtrichiliaelegansaqueousleafextracts AT benenciafabian immunomodulatoryactivitiesofcedrelalilloiandtrichiliaelegansaqueousleafextracts AT coulombiefelixcarlos immunomodulatoryactivitiesofcedrelalilloiandtrichiliaelegansaqueousleafextracts |
| _version_ |
1768543279798812672 |