Synthesis of [131-I]-iodinated quercetin

Two iodination procedures via thallation were applied to quercetin leading to the formation of 2'-iodoquercetin and 2',6,8-triiodoquercetin; their structures being elucidated by FT-IR and NMR spectral analysis. The preparation of mono- and polyiodinated products is discussed here on the ba...

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Autor principal: Pomilio, Alicia Beatriz
Publicado: 1997
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v39_n11_p927_Barolli
http://hdl.handle.net/20.500.12110/paper_03624803_v39_n11_p927_Barolli
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spelling paper:paper_03624803_v39_n11_p927_Barolli2023-06-08T15:35:11Z Synthesis of [131-I]-iodinated quercetin Pomilio, Alicia Beatriz 131-iodine 2',6,8- triiodoquercetin 2'-iodoquercetin Iodination Quercetin Radiolabelling iodine 131 quercetin antioxidant activity article drug structure drug synthesis iodination oxidative stress Two iodination procedures via thallation were applied to quercetin leading to the formation of 2'-iodoquercetin and 2',6,8-triiodoquercetin; their structures being elucidated by FT-IR and NMR spectral analysis. The preparation of mono- and polyiodinated products is discussed here on the basis of the experimental details and spectral data. This is the first report on the radiolabelling of quercetin, which is here selectively performed with 131-iodine. The radiochemical purity was of 99%. Fil:Pomilio, A.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v39_n11_p927_Barolli http://hdl.handle.net/20.500.12110/paper_03624803_v39_n11_p927_Barolli
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 131-iodine
2',6,8- triiodoquercetin
2'-iodoquercetin
Iodination
Quercetin
Radiolabelling
iodine 131
quercetin
antioxidant activity
article
drug structure
drug synthesis
iodination
oxidative stress
spellingShingle 131-iodine
2',6,8- triiodoquercetin
2'-iodoquercetin
Iodination
Quercetin
Radiolabelling
iodine 131
quercetin
antioxidant activity
article
drug structure
drug synthesis
iodination
oxidative stress
Pomilio, Alicia Beatriz
Synthesis of [131-I]-iodinated quercetin
topic_facet 131-iodine
2',6,8- triiodoquercetin
2'-iodoquercetin
Iodination
Quercetin
Radiolabelling
iodine 131
quercetin
antioxidant activity
article
drug structure
drug synthesis
iodination
oxidative stress
description Two iodination procedures via thallation were applied to quercetin leading to the formation of 2'-iodoquercetin and 2',6,8-triiodoquercetin; their structures being elucidated by FT-IR and NMR spectral analysis. The preparation of mono- and polyiodinated products is discussed here on the basis of the experimental details and spectral data. This is the first report on the radiolabelling of quercetin, which is here selectively performed with 131-iodine. The radiochemical purity was of 99%.
author Pomilio, Alicia Beatriz
author_facet Pomilio, Alicia Beatriz
author_sort Pomilio, Alicia Beatriz
title Synthesis of [131-I]-iodinated quercetin
title_short Synthesis of [131-I]-iodinated quercetin
title_full Synthesis of [131-I]-iodinated quercetin
title_fullStr Synthesis of [131-I]-iodinated quercetin
title_full_unstemmed Synthesis of [131-I]-iodinated quercetin
title_sort synthesis of [131-i]-iodinated quercetin
publishDate 1997
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v39_n11_p927_Barolli
http://hdl.handle.net/20.500.12110/paper_03624803_v39_n11_p927_Barolli
work_keys_str_mv AT pomilioaliciabeatriz synthesisof131iiodinatedquercetin
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