Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes

Biological and chemical characteristics of 99mTc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these 99mTc‐complexes as dopamine re...

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Detalles Bibliográficos
Autores principales:	Vitale, Arturo Alberto, Calviño, María Ana, Ferrari, Carina Cintia, Pomilio, Alicia Beatriz
Publicado:	1995
Materias:	2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v36_n6_p509_Vitale http://hdl.handle.net/20.500.12110/paper_03624803_v36_n6_p509_Vitale
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_03624803_v36_n6_p509_Vitale
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spelling	paper:paper_03624803_v36_n6_p509_Vitale2023-06-08T15:35:11Z Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes Vitale, Arturo Alberto Calviño, María Ana Ferrari, Carina Cintia Pomilio, Alicia Beatriz 2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia Biological and chemical characteristics of 99mTc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these 99mTc‐complexes as dopamine receptor radioligands was also performed. Net charges at each atom were also calculated by a semiempirical ZINDO/1 method for comparison of free ligands' parameters with those of the respective technetium‐complexes. Copyright © 1995 John Wiley & Sons, Ltd. Fil:Vitale, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Calvino, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Ferrari, C.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pomilio, A.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1995 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v36_n6_p509_Vitale http://hdl.handle.net/20.500.12110/paper_03624803_v36_n6_p509_Vitale
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia
spellingShingle	2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia Vitale, Arturo Alberto Calviño, María Ana Ferrari, Carina Cintia Pomilio, Alicia Beatriz Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
topic_facet	2‐(2‐Amino‐4,5‐dimethoxyphenyl)ethylamine 2‐(3,4‐Dimethoxyphenyl)‐ethylamine 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine 99m‐Technetium complexes Biodistribution Preparation semiempirical ZINDO/1 calculations phenethylamine derivative technetium 99m technetium complex animal experiment article brain controlled study drug distribution drug structure drug synthesis electrophoresis female intracerebral drug administration isotope labeling nonhuman radiochromatography rat Animalia
description	Biological and chemical characteristics of 99mTc‐phenethylamines complexes are presented. 2‐(4,5‐Dimethoxy‐2‐nitrophenyl)ethylamine, 2‐(3,4‐dimethoxyphenyl)ethylamine and 2‐(2‐amino‐4,5‐dimethoxyphenyl)‐ethylamine were used as ligands. A preliminary evaluation of these 99mTc‐complexes as dopamine receptor radioligands was also performed. Net charges at each atom were also calculated by a semiempirical ZINDO/1 method for comparison of free ligands' parameters with those of the respective technetium‐complexes. Copyright © 1995 John Wiley & Sons, Ltd.
author	Vitale, Arturo Alberto Calviño, María Ana Ferrari, Carina Cintia Pomilio, Alicia Beatriz
author_facet	Vitale, Arturo Alberto Calviño, María Ana Ferrari, Carina Cintia Pomilio, Alicia Beatriz
author_sort	Vitale, Arturo Alberto
title	Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
title_short	Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
title_full	Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
title_fullStr	Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
title_full_unstemmed	Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
title_sort	preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes
publishDate	1995
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v36_n6_p509_Vitale http://hdl.handle.net/20.500.12110/paper_03624803_v36_n6_p509_Vitale
work_keys_str_mv	AT vitalearturoalberto preparationandbiologicalevaluationoftechnetium99mphenylethylaminecomplexes AT calvinomariaana preparationandbiologicalevaluationoftechnetium99mphenylethylaminecomplexes AT ferraricarinacintia preparationandbiologicalevaluationoftechnetium99mphenylethylaminecomplexes AT pomilioaliciabeatriz preparationandbiologicalevaluationoftechnetium99mphenylethylaminecomplexes
_version_	1768545466273759232

Preparation and biological evaluation of technetium‐99m‐phenylethylamine complexes

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