The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets

Perhaps for being considered mere megakaryocyte cytoplasmic debris responsible for wound repair alone, platelets have had a secondary role when compared to other cellular blood components. However, in the last 20 years we have learned much more about these fascinating cells, which have slowly regain...

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Detalles Bibliográficos
Autor principal: Pozner, Roberto Gabriel
Publicado: 2016
Materias:
Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v50_n2_p233_Rivadeneyra
http://hdl.handle.net/20.500.12110/paper_03252957_v50_n2_p233_Rivadeneyra
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_03252957_v50_n2_p233_Rivadeneyra
record_format dspace
spelling paper:paper_03252957_v50_n2_p233_Rivadeneyra2025-07-30T18:09:48Z The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets Pozner, Roberto Gabriel Chemokines Cytokines Hematopoiesis Hemostasis Megakaryocytes Megakaryopoiesis Platelet biogenesis Platelets Thrombopoiesis Thrombosis Perhaps for being considered mere megakaryocyte cytoplasmic debris responsible for wound repair alone, platelets have had a secondary role when compared to other cellular blood components. However, in the last 20 years we have learned much more about these fascinating cells, which have slowly regained a prominent place in hematology. This review discusses the most outstanding and novel contributions on platelet biogenesis, its regulation by the bone marrow microenvironment and humoral factors, analyzing from megakaryocyte generation to platelet release. Fil:Pozner, R.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v50_n2_p233_Rivadeneyra http://hdl.handle.net/20.500.12110/paper_03252957_v50_n2_p233_Rivadeneyra
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
spellingShingle Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
Pozner, Roberto Gabriel
The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
topic_facet Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
description Perhaps for being considered mere megakaryocyte cytoplasmic debris responsible for wound repair alone, platelets have had a secondary role when compared to other cellular blood components. However, in the last 20 years we have learned much more about these fascinating cells, which have slowly regained a prominent place in hematology. This review discusses the most outstanding and novel contributions on platelet biogenesis, its regulation by the bone marrow microenvironment and humoral factors, analyzing from megakaryocyte generation to platelet release.
author Pozner, Roberto Gabriel
author_facet Pozner, Roberto Gabriel
author_sort Pozner, Roberto Gabriel
title The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_short The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_full The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_fullStr The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_full_unstemmed The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_sort birth of a platelet: a trip from bone marrow megakaryocytes to circulating platelets
publishDate 2016
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v50_n2_p233_Rivadeneyra
http://hdl.handle.net/20.500.12110/paper_03252957_v50_n2_p233_Rivadeneyra
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