The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

The MetaCyc database (MetaCyc.org) is a freely accessible comprehensive database describing metabolic pathways and enzymes from all domains of life. The majority of MetaCyc pathways are small-molecule metabolic pathways that have been experimentally determined. MetaCyc contains more than 2400 pathwa...

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Publicado: 2016
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03051048_v44_nD1_pD471_Caspi
http://hdl.handle.net/20.500.12110/paper_03051048_v44_nD1_pD471_Caspi
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spelling paper:paper_03051048_v44_nD1_pD471_Caspi2025-07-30T18:08:07Z The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases algorithm Article electron transport factual database gene sequence genetic database human metabolism metabolite molecular weight nonhuman operon phenotype priority journal quality control chemical database genetics genome Internet software enzyme Databases, Chemical Databases, Genetic Electron Transport Enzymes Genome Internet Metabolic Networks and Pathways Software The MetaCyc database (MetaCyc.org) is a freely accessible comprehensive database describing metabolic pathways and enzymes from all domains of life. The majority of MetaCyc pathways are small-molecule metabolic pathways that have been experimentally determined. MetaCyc contains more than 2400 pathways derived from >46 000 publications, and is the largest curated collection of metabolic pathways. BioCyc (BioCyc.org) is a collection of 5700 organism-specific Pathway/Genome Databases (PGDBs), each containing the full genome and predicted metabolic network of one organism, including metabolites, enzymes, reactions, metabolic pathways, predicted operons, transport systems, and pathway-hole fillers. The BioCyc website offers a variety of tools for querying and analyzing PGDBs, including Omics Viewers and tools for comparative analysis. This article provides an update of new developments in MetaCyc and BioCyc during the last two years, including addition of Gibbs free energy values for compounds and reactions; redesign of the primary gene/protein page; addition of a tool for creating diagrams containing multiple linked pathways; several new search capabilities, including searching for genes based on sequence patterns, searching for databases based on an organism's phenotypes, and a cross-organism search; and a metabolite identifier translation service. © The Author(s) 2015. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03051048_v44_nD1_pD471_Caspi http://hdl.handle.net/20.500.12110/paper_03051048_v44_nD1_pD471_Caspi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic algorithm
Article
electron transport
factual database
gene sequence
genetic database
human
metabolism
metabolite
molecular weight
nonhuman
operon
phenotype
priority journal
quality control
chemical database
genetics
genome
Internet
software
enzyme
Databases, Chemical
Databases, Genetic
Electron Transport
Enzymes
Genome
Internet
Metabolic Networks and Pathways
Software
spellingShingle algorithm
Article
electron transport
factual database
gene sequence
genetic database
human
metabolism
metabolite
molecular weight
nonhuman
operon
phenotype
priority journal
quality control
chemical database
genetics
genome
Internet
software
enzyme
Databases, Chemical
Databases, Genetic
Electron Transport
Enzymes
Genome
Internet
Metabolic Networks and Pathways
Software
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
topic_facet algorithm
Article
electron transport
factual database
gene sequence
genetic database
human
metabolism
metabolite
molecular weight
nonhuman
operon
phenotype
priority journal
quality control
chemical database
genetics
genome
Internet
software
enzyme
Databases, Chemical
Databases, Genetic
Electron Transport
Enzymes
Genome
Internet
Metabolic Networks and Pathways
Software
description The MetaCyc database (MetaCyc.org) is a freely accessible comprehensive database describing metabolic pathways and enzymes from all domains of life. The majority of MetaCyc pathways are small-molecule metabolic pathways that have been experimentally determined. MetaCyc contains more than 2400 pathways derived from >46 000 publications, and is the largest curated collection of metabolic pathways. BioCyc (BioCyc.org) is a collection of 5700 organism-specific Pathway/Genome Databases (PGDBs), each containing the full genome and predicted metabolic network of one organism, including metabolites, enzymes, reactions, metabolic pathways, predicted operons, transport systems, and pathway-hole fillers. The BioCyc website offers a variety of tools for querying and analyzing PGDBs, including Omics Viewers and tools for comparative analysis. This article provides an update of new developments in MetaCyc and BioCyc during the last two years, including addition of Gibbs free energy values for compounds and reactions; redesign of the primary gene/protein page; addition of a tool for creating diagrams containing multiple linked pathways; several new search capabilities, including searching for genes based on sequence patterns, searching for databases based on an organism's phenotypes, and a cross-organism search; and a metabolite identifier translation service. © The Author(s) 2015.
title The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
title_short The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
title_full The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
title_fullStr The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
title_full_unstemmed The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
title_sort metacyc database of metabolic pathways and enzymes and the biocyc collection of pathway/genome databases
publishDate 2016
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03051048_v44_nD1_pD471_Caspi
http://hdl.handle.net/20.500.12110/paper_03051048_v44_nD1_pD471_Caspi
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