1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids

Mostrar todas las versiones(2)

1H-1H NMR couplings through four bonds ( 4JH-H) involving cyclopropane hydrogens were calculated for model compounds by semiempirical methods and used for the 13C and 1H NMR spectral assignment of 17,18-cyclosteroids. The couplings (4JHH) between cyclopropyl and non-cyclopropyl hydrogens follow an a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sproviero, Eduardo Marcelo, Ferrara, Andrés, Contreras, Rubén Horacio, Burton, Gerardo
Publicado: 1996
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009580_v5_n_p933_Sproviero
http://hdl.handle.net/20.500.12110/paper_03009580_v5_n_p933_Sproviero
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_03009580_v5_n_p933_Sproviero
record_format dspace
spelling paper:paper_03009580_v5_n_p933_Sproviero2023-06-08T15:27:42Z 1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids Sproviero, Eduardo Marcelo Ferrara, Andrés Contreras, Rubén Horacio Burton, Gerardo 1H-1H NMR couplings through four bonds ( 4JH-H) involving cyclopropane hydrogens were calculated for model compounds by semiempirical methods and used for the 13C and 1H NMR spectral assignment of 17,18-cyclosteroids. The couplings (4JHH) between cyclopropyl and non-cyclopropyl hydrogens follow an angular dependence which resembles that of allylic couplings. Solution conformations of rings C-D and the side-chain of 17,18-cyclopregnanes were determined from semiempirical molecular orbital calculations, three and four bond 1H-1H coupling constants and NOE measurements. Fil:Sproviero, E.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Ferrara, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Contreras, R.H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Burton, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1996 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009580_v5_n_p933_Sproviero http://hdl.handle.net/20.500.12110/paper_03009580_v5_n_p933_Sproviero
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description 1H-1H NMR couplings through four bonds ( 4JH-H) involving cyclopropane hydrogens were calculated for model compounds by semiempirical methods and used for the 13C and 1H NMR spectral assignment of 17,18-cyclosteroids. The couplings (4JHH) between cyclopropyl and non-cyclopropyl hydrogens follow an angular dependence which resembles that of allylic couplings. Solution conformations of rings C-D and the side-chain of 17,18-cyclopregnanes were determined from semiempirical molecular orbital calculations, three and four bond 1H-1H coupling constants and NOE measurements.
author Sproviero, Eduardo Marcelo
Ferrara, Andrés
Contreras, Rubén Horacio
Burton, Gerardo
spellingShingle Sproviero, Eduardo Marcelo
Ferrara, Andrés
Contreras, Rubén Horacio
Burton, Gerardo
1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids
author_facet Sproviero, Eduardo Marcelo
Ferrara, Andrés
Contreras, Rubén Horacio
Burton, Gerardo
author_sort Sproviero, Eduardo Marcelo
title 1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids
title_short 1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids
title_full 1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids
title_fullStr 1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids
title_full_unstemmed 1H-1H Long range couplings in fused cyclopropanes. NMR spectral assignment and conformation of 17,18-cyclosteroids
title_sort 1h-1h long range couplings in fused cyclopropanes. nmr spectral assignment and conformation of 17,18-cyclosteroids
publishDate 1996
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009580_v5_n_p933_Sproviero
http://hdl.handle.net/20.500.12110/paper_03009580_v5_n_p933_Sproviero
work_keys_str_mv AT sprovieroeduardomarcelo 1h1hlongrangecouplingsinfusedcyclopropanesnmrspectralassignmentandconformationof1718cyclosteroids
AT ferraraandres 1h1hlongrangecouplingsinfusedcyclopropanesnmrspectralassignmentandconformationof1718cyclosteroids
AT contrerasrubenhoracio 1h1hlongrangecouplingsinfusedcyclopropanesnmrspectralassignmentandconformationof1718cyclosteroids
AT burtongerardo 1h1hlongrangecouplingsinfusedcyclopropanesnmrspectralassignmentandconformationof1718cyclosteroids
_version_ 1768545187634610176

Ejemplares similares