Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study

Introduction: Vascular reactivity (VR) can be defined as the arterial ability to react to vasoactive stimulus in terms of vasodilator or vasoconstrictor responses, where blood vessel tone is determined both by smooth muscle and endothelial functions (EF). Flow mediated dilation (FMD) and Peripheral...

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Publicado: 2017
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0277786X_v10160_n_p_PerezLopez
http://hdl.handle.net/20.500.12110/paper_0277786X_v10160_n_p_PerezLopez
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spelling paper:paper_0277786X_v10160_n_p_PerezLopez2023-06-08T15:26:08Z Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study Applanation tonometry Pressure-Diameter loop Pulse transit time Real-time system Ultrasound Vascular reactivity Bioinformatics Blood vessels Data visualization Digital storage Interactive computer systems Real time systems Ultrasonics Applanation tonometry B-mode ultrasound images Endothelial function Flow mediated dilation Involuntary movements Peripheral arterial tonometry Pulse transit time Simultaneous measurement Ultrasonic applications Introduction: Vascular reactivity (VR) can be defined as the arterial ability to react to vasoactive stimulus in terms of vasodilator or vasoconstrictor responses, where blood vessel tone is determined both by smooth muscle and endothelial functions (EF). Flow mediated dilation (FMD) and Peripheral Arterial Tonometry (PAT) measurements are recognized as the most relevant techniques for VR and EF evaluation. Objective: To design an integrated system for vascular analysis based on the limitations reported in FMD technique and incorporating PAT as a simultaneous measure. Materials and Methods: A complete software platform and a specific fastening system were proposed, in order to obtain simultaneous measurements of continuous arterial pressure (by applying the applanation tonometry technique) and continuous vessel diameter variations (by processing B-mode ultrasound images) at the same vascular site. Results: Beat to beat pressure-diameter loops were obtained, along with the assessment of stiffness indices and pulse transit time values. The volunteer who used the system felt comfortable and relaxed, unworried about making about involuntary movements Conclusion: A preliminary study was carried out using this new module designed for the acquisition, realtime processing, visualization and storage of vascular behavior related data. © 2017 SPIE. 2017 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0277786X_v10160_n_p_PerezLopez http://hdl.handle.net/20.500.12110/paper_0277786X_v10160_n_p_PerezLopez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Applanation tonometry
Pressure-Diameter loop
Pulse transit time
Real-time system
Ultrasound
Vascular reactivity
Bioinformatics
Blood vessels
Data visualization
Digital storage
Interactive computer systems
Real time systems
Ultrasonics
Applanation tonometry
B-mode ultrasound images
Endothelial function
Flow mediated dilation
Involuntary movements
Peripheral arterial tonometry
Pulse transit time
Simultaneous measurement
Ultrasonic applications
spellingShingle Applanation tonometry
Pressure-Diameter loop
Pulse transit time
Real-time system
Ultrasound
Vascular reactivity
Bioinformatics
Blood vessels
Data visualization
Digital storage
Interactive computer systems
Real time systems
Ultrasonics
Applanation tonometry
B-mode ultrasound images
Endothelial function
Flow mediated dilation
Involuntary movements
Peripheral arterial tonometry
Pulse transit time
Simultaneous measurement
Ultrasonic applications
Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
topic_facet Applanation tonometry
Pressure-Diameter loop
Pulse transit time
Real-time system
Ultrasound
Vascular reactivity
Bioinformatics
Blood vessels
Data visualization
Digital storage
Interactive computer systems
Real time systems
Ultrasonics
Applanation tonometry
B-mode ultrasound images
Endothelial function
Flow mediated dilation
Involuntary movements
Peripheral arterial tonometry
Pulse transit time
Simultaneous measurement
Ultrasonic applications
description Introduction: Vascular reactivity (VR) can be defined as the arterial ability to react to vasoactive stimulus in terms of vasodilator or vasoconstrictor responses, where blood vessel tone is determined both by smooth muscle and endothelial functions (EF). Flow mediated dilation (FMD) and Peripheral Arterial Tonometry (PAT) measurements are recognized as the most relevant techniques for VR and EF evaluation. Objective: To design an integrated system for vascular analysis based on the limitations reported in FMD technique and incorporating PAT as a simultaneous measure. Materials and Methods: A complete software platform and a specific fastening system were proposed, in order to obtain simultaneous measurements of continuous arterial pressure (by applying the applanation tonometry technique) and continuous vessel diameter variations (by processing B-mode ultrasound images) at the same vascular site. Results: Beat to beat pressure-diameter loops were obtained, along with the assessment of stiffness indices and pulse transit time values. The volunteer who used the system felt comfortable and relaxed, unworried about making about involuntary movements Conclusion: A preliminary study was carried out using this new module designed for the acquisition, realtime processing, visualization and storage of vascular behavior related data. © 2017 SPIE.
title Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
title_short Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
title_full Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
title_fullStr Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
title_full_unstemmed Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
title_sort real-time vascular response assessment by means of a dual pressure-diameter device: a preliminary study
publishDate 2017
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0277786X_v10160_n_p_PerezLopez
http://hdl.handle.net/20.500.12110/paper_0277786X_v10160_n_p_PerezLopez
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