The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
ABSTRACT: The antigens isolated from the trichloroacetic acid soluble fraction of human seminal plasma show a polymodal molecular weight heterodispersion. The molecular weights corresponding to the modes of the distribution have limiting values of 2,500‐57,000. Previous results obtained by polyacryl...
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1981
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02717352_v1_n5_p266_DECEREZO http://hdl.handle.net/20.500.12110/paper_02717352_v1_n5_p266_DECEREZO |
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paper:paper_02717352_v1_n5_p266_DECEREZO2023-06-08T15:24:59Z The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma Cerezo, Alberto Saúl antigens human seminal plasma Molecular weight heterodispersion trichloroacetic soluble fraction trichloroacetic acid male genital system normal human sperm ABSTRACT: The antigens isolated from the trichloroacetic acid soluble fraction of human seminal plasma show a polymodal molecular weight heterodispersion. The molecular weights corresponding to the modes of the distribution have limiting values of 2,500‐57,000. Previous results obtained by polyacrylamide gel and cellogel electrophoresis, immunodiffusion and Immunoelectrophoresis, and ultracentrifugation analysis, which suggested homogeneity, were explained by the formation of molecular aggregates, which would also explain why the smaller fragments were not lost during the dialysis carried out in the preparation and purification of the samples. The average molecular weight of the antigens, determined by gel permeation chromatography and using the equation of Svedberg, is in the range of 10,000–40,000. It is suggested that the polymodal heterodispersion together with the associating‐dissociating properties of these products is used to control their immunological behavior. 1981 Munksgaard Fil:CEREZO, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1981 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02717352_v1_n5_p266_DECEREZO http://hdl.handle.net/20.500.12110/paper_02717352_v1_n5_p266_DECEREZO |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
antigens human seminal plasma Molecular weight heterodispersion trichloroacetic soluble fraction trichloroacetic acid male genital system normal human sperm |
spellingShingle |
antigens human seminal plasma Molecular weight heterodispersion trichloroacetic soluble fraction trichloroacetic acid male genital system normal human sperm Cerezo, Alberto Saúl The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma |
topic_facet |
antigens human seminal plasma Molecular weight heterodispersion trichloroacetic soluble fraction trichloroacetic acid male genital system normal human sperm |
description |
ABSTRACT: The antigens isolated from the trichloroacetic acid soluble fraction of human seminal plasma show a polymodal molecular weight heterodispersion. The molecular weights corresponding to the modes of the distribution have limiting values of 2,500‐57,000. Previous results obtained by polyacrylamide gel and cellogel electrophoresis, immunodiffusion and Immunoelectrophoresis, and ultracentrifugation analysis, which suggested homogeneity, were explained by the formation of molecular aggregates, which would also explain why the smaller fragments were not lost during the dialysis carried out in the preparation and purification of the samples. The average molecular weight of the antigens, determined by gel permeation chromatography and using the equation of Svedberg, is in the range of 10,000–40,000. It is suggested that the polymodal heterodispersion together with the associating‐dissociating properties of these products is used to control their immunological behavior. 1981 Munksgaard |
author |
Cerezo, Alberto Saúl |
author_facet |
Cerezo, Alberto Saúl |
author_sort |
Cerezo, Alberto Saúl |
title |
The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma |
title_short |
The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma |
title_full |
The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma |
title_fullStr |
The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma |
title_full_unstemmed |
The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma |
title_sort |
molecular weights and molecular weight heterodispersion of some antigens from the trichloroacetic acid soluble fraction of human seminal plasma |
publishDate |
1981 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02717352_v1_n5_p266_DECEREZO http://hdl.handle.net/20.500.12110/paper_02717352_v1_n5_p266_DECEREZO |
work_keys_str_mv |
AT cerezoalbertosaul themolecularweightsandmolecularweightheterodispersionofsomeantigensfromthetrichloroaceticacidsolublefractionofhumanseminalplasma AT cerezoalbertosaul molecularweightsandmolecularweightheterodispersionofsomeantigensfromthetrichloroaceticacidsolublefractionofhumanseminalplasma |
_version_ |
1768545553579245568 |