Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
Balb/c mice fed a diet containing 20% fish oil developed herpes stromal keratitis earlier and with more severe lesions than control group. Peritoneal macrophages oxidative metabolism and intrinsic antiviral activity are not modified by diet manipulation but nitric oxide production was significantly...
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2001
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02715317_v21_n1-2_p229_Courreges http://hdl.handle.net/20.500.12110/paper_02715317_v21_n1-2_p229_Courreges |
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paper:paper_02715317_v21_n1-2_p229_Courreges2023-06-08T15:24:58Z Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection Courréges, María Cecilia Benencia, Fabián Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1 Balb/c mice fed a diet containing 20% fish oil developed herpes stromal keratitis earlier and with more severe lesions than control group. Peritoneal macrophages oxidative metabolism and intrinsic antiviral activity are not modified by diet manipulation but nitric oxide production was significantly impaired. On the contrary, splenic lymphocytes proliferation stimulated "ex vivo" by heat inactivated HSV-1 is significantly increased as well as delayed type hypersensitivity. So, taking into account that herpes stromal keratitis is mediated by T cells, the effect of diet over these cells could be responsible for the observed exacerbation of the disease. © 2001 Elsevier Science Inc. Fil:Courrèges, M.Cecilia Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Benencia, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2001 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02715317_v21_n1-2_p229_Courreges http://hdl.handle.net/20.500.12110/paper_02715317_v21_n1-2_p229_Courreges |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1 |
| spellingShingle |
Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1 Courréges, María Cecilia Benencia, Fabián Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection |
| topic_facet |
Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1 |
| description |
Balb/c mice fed a diet containing 20% fish oil developed herpes stromal keratitis earlier and with more severe lesions than control group. Peritoneal macrophages oxidative metabolism and intrinsic antiviral activity are not modified by diet manipulation but nitric oxide production was significantly impaired. On the contrary, splenic lymphocytes proliferation stimulated "ex vivo" by heat inactivated HSV-1 is significantly increased as well as delayed type hypersensitivity. So, taking into account that herpes stromal keratitis is mediated by T cells, the effect of diet over these cells could be responsible for the observed exacerbation of the disease. © 2001 Elsevier Science Inc. |
| author |
Courréges, María Cecilia Benencia, Fabián |
| author_facet |
Courréges, María Cecilia Benencia, Fabián |
| author_sort |
Courréges, María Cecilia |
| title |
Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection |
| title_short |
Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection |
| title_full |
Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection |
| title_fullStr |
Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection |
| title_full_unstemmed |
Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection |
| title_sort |
effect of dietary fish oil on mouse ocular herpes simplex type i infection |
| publishDate |
2001 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02715317_v21_n1-2_p229_Courreges http://hdl.handle.net/20.500.12110/paper_02715317_v21_n1-2_p229_Courreges |
| work_keys_str_mv |
AT courregesmariacecilia effectofdietaryfishoilonmouseocularherpessimplextypeiinfection AT benenciafabian effectofdietaryfishoilonmouseocularherpessimplextypeiinfection |
| _version_ |
1768545002967793664 |