Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives

We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy an...

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Detalles Bibliográficos
Publicado:	2010
Materias:	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01035053_v21_n1_p43_Scorzo http://hdl.handle.net/20.500.12110/paper_01035053_v21_n1_p43_Scorzo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_01035053_v21_n1_p43_Scorzo
record_format	dspace
spelling	paper:paper_01035053_v21_n1_p43_Scorzo2023-06-08T15:10:23Z Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy and elemental analysis. The new heterocycles and their derivatives were evaluated as inhibitors of acetylcholinesterase enzyme. © 2010 Sociedade Brasileira de Química. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01035053_v21_n1_p43_Scorzo http://hdl.handle.net/20.500.12110/paper_01035053_v21_n1_p43_Scorzo
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds
spellingShingle	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
topic_facet	Acetylcholinesterase Alzheimeŕs disease Cycloaddition D-glyceraldehyde Heterocyclic compounds
description	We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy and elemental analysis. The new heterocycles and their derivatives were evaluated as inhibitors of acetylcholinesterase enzyme. © 2010 Sociedade Brasileira de Química.
title	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_short	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_full	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_fullStr	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_full_unstemmed	Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives
title_sort	synthesis and antiacetylcholinesterase activity of new d-glyceraldehyde heterocyclic derivatives
publishDate	2010
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01035053_v21_n1_p43_Scorzo http://hdl.handle.net/20.500.12110/paper_01035053_v21_n1_p43_Scorzo
_version_	1768546109228056576

Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives

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