Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina
In Argentina, most dairy cows with endometritis are treated with prostaglandin (PGF2α or its analogs) and insemination is withheld until there are no signs of endometritis. The objective of the present study was to evaluate if this method of managing endometritis enhances reproductive performance. T...
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2005
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0093691X_v63_n5_p1266_Mejia http://hdl.handle.net/20.500.12110/paper_0093691X_v63_n5_p1266_Mejia |
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paper:paper_0093691X_v63_n5_p1266_Mejia2023-06-08T15:09:01Z Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina Dairy cow Endometritis PGF2α Reproductive performance Tiaprost Bos taurus drug derivative prostaglandin F prostaglandin F2 alpha thiophene derivative tiaprost animal animal disease Argentina article artificial insemination cattle cattle disease endometritis estrus female fertilization palpation parity pathology pregnancy rectum reproduction statistical model time uterus Animals Argentina Cattle Cattle Diseases Dinoprost Endometritis Estrus Female Fertilization Insemination, Artificial Linear Models Palpation Parity Pregnancy Prostaglandins F, Synthetic Rectum Reproduction Thiophenes Time Factors Uterus In Argentina, most dairy cows with endometritis are treated with prostaglandin (PGF2α or its analogs) and insemination is withheld until there are no signs of endometritis. The objective of the present study was to evaluate if this method of managing endometritis enhances reproductive performance. Three experiments were conducted over 4 years in a large farm in the west of Buenos Aires province. In Experiment 1, half of the cows diagnosed with endometritis (>1.5-fold difference in diameter of uterine horns, as determined by rectal palpation) received standard endometritis management (treatment with tiaprost, a PGF2α analog, rectal palpation every 20 days, and withholding of AI until endometritis apparently resolved) and the other half was untreated, with AI at the first estrus after the voluntary waiting period. Untreated cows were inseminated and conceived 20 days earlier than treated cows, and the pregnancy rate by Day 90 postpartum was higher in the untreated group. In Experiment 2, cows with endometritis were divided into four groups according to the severity of symptoms; within each group, cows were allocated to treatment or control, as in Experiment 1. Although first service conception rate decreased as endometritis severity increased, reproductive performance in treated versus control cows was similar to that of Experiment 1 (with no interaction due to degree of endometritis). Re-evaluation of the treated cow (to confirm uterine "normality") may have been responsible for the delay in conception in both experiments. The objective of Experiment 3 was to determine the effects of tiaprost treatment on clinically normal postpartum cows (no evidence of endometritis). Tiaprost treatment reduced the interval from calving to conception in multiparous cows, but it delayed conception and reduced the conception rate in primiparous cows. In conclusion, treatment with tiaprost impaired reproductive performance in primiparous cows (in the absence of endometritis). Furthermore, the standard treatment for endometritis (treatment with a prostaglandin analog and withholding insemination until clinical signs abated) impaired reproductive performance and increased costs. © 2004 Elsevier Inc. All rights reserved. 2005 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0093691X_v63_n5_p1266_Mejia http://hdl.handle.net/20.500.12110/paper_0093691X_v63_n5_p1266_Mejia |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Dairy cow Endometritis PGF2α Reproductive performance Tiaprost Bos taurus drug derivative prostaglandin F prostaglandin F2 alpha thiophene derivative tiaprost animal animal disease Argentina article artificial insemination cattle cattle disease endometritis estrus female fertilization palpation parity pathology pregnancy rectum reproduction statistical model time uterus Animals Argentina Cattle Cattle Diseases Dinoprost Endometritis Estrus Female Fertilization Insemination, Artificial Linear Models Palpation Parity Pregnancy Prostaglandins F, Synthetic Rectum Reproduction Thiophenes Time Factors Uterus |
| spellingShingle |
Dairy cow Endometritis PGF2α Reproductive performance Tiaprost Bos taurus drug derivative prostaglandin F prostaglandin F2 alpha thiophene derivative tiaprost animal animal disease Argentina article artificial insemination cattle cattle disease endometritis estrus female fertilization palpation parity pathology pregnancy rectum reproduction statistical model time uterus Animals Argentina Cattle Cattle Diseases Dinoprost Endometritis Estrus Female Fertilization Insemination, Artificial Linear Models Palpation Parity Pregnancy Prostaglandins F, Synthetic Rectum Reproduction Thiophenes Time Factors Uterus Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina |
| topic_facet |
Dairy cow Endometritis PGF2α Reproductive performance Tiaprost Bos taurus drug derivative prostaglandin F prostaglandin F2 alpha thiophene derivative tiaprost animal animal disease Argentina article artificial insemination cattle cattle disease endometritis estrus female fertilization palpation parity pathology pregnancy rectum reproduction statistical model time uterus Animals Argentina Cattle Cattle Diseases Dinoprost Endometritis Estrus Female Fertilization Insemination, Artificial Linear Models Palpation Parity Pregnancy Prostaglandins F, Synthetic Rectum Reproduction Thiophenes Time Factors Uterus |
| description |
In Argentina, most dairy cows with endometritis are treated with prostaglandin (PGF2α or its analogs) and insemination is withheld until there are no signs of endometritis. The objective of the present study was to evaluate if this method of managing endometritis enhances reproductive performance. Three experiments were conducted over 4 years in a large farm in the west of Buenos Aires province. In Experiment 1, half of the cows diagnosed with endometritis (>1.5-fold difference in diameter of uterine horns, as determined by rectal palpation) received standard endometritis management (treatment with tiaprost, a PGF2α analog, rectal palpation every 20 days, and withholding of AI until endometritis apparently resolved) and the other half was untreated, with AI at the first estrus after the voluntary waiting period. Untreated cows were inseminated and conceived 20 days earlier than treated cows, and the pregnancy rate by Day 90 postpartum was higher in the untreated group. In Experiment 2, cows with endometritis were divided into four groups according to the severity of symptoms; within each group, cows were allocated to treatment or control, as in Experiment 1. Although first service conception rate decreased as endometritis severity increased, reproductive performance in treated versus control cows was similar to that of Experiment 1 (with no interaction due to degree of endometritis). Re-evaluation of the treated cow (to confirm uterine "normality") may have been responsible for the delay in conception in both experiments. The objective of Experiment 3 was to determine the effects of tiaprost treatment on clinically normal postpartum cows (no evidence of endometritis). Tiaprost treatment reduced the interval from calving to conception in multiparous cows, but it delayed conception and reduced the conception rate in primiparous cows. In conclusion, treatment with tiaprost impaired reproductive performance in primiparous cows (in the absence of endometritis). Furthermore, the standard treatment for endometritis (treatment with a prostaglandin analog and withholding insemination until clinical signs abated) impaired reproductive performance and increased costs. © 2004 Elsevier Inc. All rights reserved. |
| title |
Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina |
| title_short |
Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina |
| title_full |
Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina |
| title_fullStr |
Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina |
| title_full_unstemmed |
Endometritis treatment with a PGF2α analog does not improve reproductive performance in a large dairy herd in Argentina |
| title_sort |
endometritis treatment with a pgf2α analog does not improve reproductive performance in a large dairy herd in argentina |
| publishDate |
2005 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0093691X_v63_n5_p1266_Mejia http://hdl.handle.net/20.500.12110/paper_0093691X_v63_n5_p1266_Mejia |
| _version_ |
1768541885089972224 |