Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System
Rupture of abdominal aortic aneurysms (AAA) is responsible for 1–3% of all deaths among the elderly population in developed countries. A novel endograft proposes an endovascular aneurysm sealing (EVAS) system that isolates the aneurysm wall from blood flow using a polymer-filled endobag that surroun...
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2016
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906964_v44_n5_p1381_Casciaro http://hdl.handle.net/20.500.12110/paper_00906964_v44_n5_p1381_Casciaro |
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paper:paper_00906964_v44_n5_p1381_Casciaro2023-06-08T15:07:52Z Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System Abdominal aorta Endograft Endovascular repair Geometrical deformed model Nellix device Balloons Computerized tomography Deformation Filled polymers Polymers Abdominal aorta Abdominal aortic aneurysms Balloon-expandable stents Computed tomography images Deformable surface models Endograft Endovascular repair Nellix device Blood vessels abdominal aorta aneurysm aneurysm sealing system Article clinical article clinical effectiveness computer assisted tomography controlled study endovascular aneurysm repair human mathematical computing mathematical model outcome assessment priority journal retrospective study Aortic Aneurysm, Abdominal biological model devices diagnostic imaging endovascular surgery pathophysiology procedures x-ray computed tomography Aortic Aneurysm, Abdominal Endovascular Procedures Humans Models, Cardiovascular Tomography, X-Ray Computed Rupture of abdominal aortic aneurysms (AAA) is responsible for 1–3% of all deaths among the elderly population in developed countries. A novel endograft proposes an endovascular aneurysm sealing (EVAS) system that isolates the aneurysm wall from blood flow using a polymer-filled endobag that surrounds two balloon-expandable stents. The volume of injected polymer is determined by monitoring the endobag pressure but the final AAA expansion remains unknown. We conceived and developed a fully deformable surface model for the comparison of pre-operative sac lumen size and final endobag size (measured using a follow-up scan) with the volume of injected polymer. Computed tomography images were acquired for eight patients. Aneurysms were manually and automatically segmented twice by the same observer. The injected polymer volume resulted 9% higher than the aneurysm pre-operative lumen size (p < 0.05), and 11% lower than the final follow-up endobag volume (p < 0.01). The automated method required minimal user interaction; it was fast and used a single set of parameters for all subjects. Intra-observer and manual vs. automated variability of measured volumes were 0.35 ± 2.11 and 0.07 ± 3.04 mL, respectively. Deformable surface models were used to quantify AAA size and showed that EVAS system devices tended to expand the sac lumen size. © 2015, Biomedical Engineering Society. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906964_v44_n5_p1381_Casciaro http://hdl.handle.net/20.500.12110/paper_00906964_v44_n5_p1381_Casciaro |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Abdominal aorta Endograft Endovascular repair Geometrical deformed model Nellix device Balloons Computerized tomography Deformation Filled polymers Polymers Abdominal aorta Abdominal aortic aneurysms Balloon-expandable stents Computed tomography images Deformable surface models Endograft Endovascular repair Nellix device Blood vessels abdominal aorta aneurysm aneurysm sealing system Article clinical article clinical effectiveness computer assisted tomography controlled study endovascular aneurysm repair human mathematical computing mathematical model outcome assessment priority journal retrospective study Aortic Aneurysm, Abdominal biological model devices diagnostic imaging endovascular surgery pathophysiology procedures x-ray computed tomography Aortic Aneurysm, Abdominal Endovascular Procedures Humans Models, Cardiovascular Tomography, X-Ray Computed |
spellingShingle |
Abdominal aorta Endograft Endovascular repair Geometrical deformed model Nellix device Balloons Computerized tomography Deformation Filled polymers Polymers Abdominal aorta Abdominal aortic aneurysms Balloon-expandable stents Computed tomography images Deformable surface models Endograft Endovascular repair Nellix device Blood vessels abdominal aorta aneurysm aneurysm sealing system Article clinical article clinical effectiveness computer assisted tomography controlled study endovascular aneurysm repair human mathematical computing mathematical model outcome assessment priority journal retrospective study Aortic Aneurysm, Abdominal biological model devices diagnostic imaging endovascular surgery pathophysiology procedures x-ray computed tomography Aortic Aneurysm, Abdominal Endovascular Procedures Humans Models, Cardiovascular Tomography, X-Ray Computed Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System |
topic_facet |
Abdominal aorta Endograft Endovascular repair Geometrical deformed model Nellix device Balloons Computerized tomography Deformation Filled polymers Polymers Abdominal aorta Abdominal aortic aneurysms Balloon-expandable stents Computed tomography images Deformable surface models Endograft Endovascular repair Nellix device Blood vessels abdominal aorta aneurysm aneurysm sealing system Article clinical article clinical effectiveness computer assisted tomography controlled study endovascular aneurysm repair human mathematical computing mathematical model outcome assessment priority journal retrospective study Aortic Aneurysm, Abdominal biological model devices diagnostic imaging endovascular surgery pathophysiology procedures x-ray computed tomography Aortic Aneurysm, Abdominal Endovascular Procedures Humans Models, Cardiovascular Tomography, X-Ray Computed |
description |
Rupture of abdominal aortic aneurysms (AAA) is responsible for 1–3% of all deaths among the elderly population in developed countries. A novel endograft proposes an endovascular aneurysm sealing (EVAS) system that isolates the aneurysm wall from blood flow using a polymer-filled endobag that surrounds two balloon-expandable stents. The volume of injected polymer is determined by monitoring the endobag pressure but the final AAA expansion remains unknown. We conceived and developed a fully deformable surface model for the comparison of pre-operative sac lumen size and final endobag size (measured using a follow-up scan) with the volume of injected polymer. Computed tomography images were acquired for eight patients. Aneurysms were manually and automatically segmented twice by the same observer. The injected polymer volume resulted 9% higher than the aneurysm pre-operative lumen size (p < 0.05), and 11% lower than the final follow-up endobag volume (p < 0.01). The automated method required minimal user interaction; it was fast and used a single set of parameters for all subjects. Intra-observer and manual vs. automated variability of measured volumes were 0.35 ± 2.11 and 0.07 ± 3.04 mL, respectively. Deformable surface models were used to quantify AAA size and showed that EVAS system devices tended to expand the sac lumen size. © 2015, Biomedical Engineering Society. |
title |
Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System |
title_short |
Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System |
title_full |
Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System |
title_fullStr |
Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System |
title_full_unstemmed |
Deformable Surface Model for the Evaluation of Abdominal Aortic Aneurysms Treated with an Endovascular Sealing System |
title_sort |
deformable surface model for the evaluation of abdominal aortic aneurysms treated with an endovascular sealing system |
publishDate |
2016 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906964_v44_n5_p1381_Casciaro http://hdl.handle.net/20.500.12110/paper_00906964_v44_n5_p1381_Casciaro |
_version_ |
1768541601976549376 |