Enantioselective synthesis of (+)-neplanocin F

(+)-Neplanocin F ((+)-5), a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in 14 steps. This synthetic approach employed a regioselective protection of a secondary allylic hydroxyl group over a h...

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Autores principales: Comin, María Julieta, Rodríguez, Juan Bautista
Publicado: 2002
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v58_n16_p3129_Comin
http://hdl.handle.net/20.500.12110/paper_00404020_v58_n16_p3129_Comin
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spelling paper:paper_00404020_v58_n16_p3129_Comin2023-06-08T15:04:14Z Enantioselective synthesis of (+)-neplanocin F Comin, María Julieta Rodríguez, Juan Bautista Ampullariella regularis Carbocyclic Neplanocin Nucleoside allyl compound antibiotic agent dextro ribono 1,4 lactone hydroxyl group lactone derivative neplanocin f unclassified drug article carbon nuclear magnetic resonance drug structure drug synthesis enantioselectivity priority journal proton nuclear magnetic resonance stereochemistry Actinoplanes Actinoplanes regularis (+)-Neplanocin F ((+)-5), a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in 14 steps. This synthetic approach employed a regioselective protection of a secondary allylic hydroxyl group over a homoallylic one as key step. © 2002 Elsevier Science Ltd. All rights reserved. Fil:Comin, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rodríguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2002 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v58_n16_p3129_Comin http://hdl.handle.net/20.500.12110/paper_00404020_v58_n16_p3129_Comin
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Ampullariella regularis
Carbocyclic
Neplanocin
Nucleoside
allyl compound
antibiotic agent
dextro ribono 1,4 lactone
hydroxyl group
lactone derivative
neplanocin f
unclassified drug
article
carbon nuclear magnetic resonance
drug structure
drug synthesis
enantioselectivity
priority journal
proton nuclear magnetic resonance
stereochemistry
Actinoplanes
Actinoplanes regularis
spellingShingle Ampullariella regularis
Carbocyclic
Neplanocin
Nucleoside
allyl compound
antibiotic agent
dextro ribono 1,4 lactone
hydroxyl group
lactone derivative
neplanocin f
unclassified drug
article
carbon nuclear magnetic resonance
drug structure
drug synthesis
enantioselectivity
priority journal
proton nuclear magnetic resonance
stereochemistry
Actinoplanes
Actinoplanes regularis
Comin, María Julieta
Rodríguez, Juan Bautista
Enantioselective synthesis of (+)-neplanocin F
topic_facet Ampullariella regularis
Carbocyclic
Neplanocin
Nucleoside
allyl compound
antibiotic agent
dextro ribono 1,4 lactone
hydroxyl group
lactone derivative
neplanocin f
unclassified drug
article
carbon nuclear magnetic resonance
drug structure
drug synthesis
enantioselectivity
priority journal
proton nuclear magnetic resonance
stereochemistry
Actinoplanes
Actinoplanes regularis
description (+)-Neplanocin F ((+)-5), a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone via a convergent approach in 14 steps. This synthetic approach employed a regioselective protection of a secondary allylic hydroxyl group over a homoallylic one as key step. © 2002 Elsevier Science Ltd. All rights reserved.
author Comin, María Julieta
Rodríguez, Juan Bautista
author_facet Comin, María Julieta
Rodríguez, Juan Bautista
author_sort Comin, María Julieta
title Enantioselective synthesis of (+)-neplanocin F
title_short Enantioselective synthesis of (+)-neplanocin F
title_full Enantioselective synthesis of (+)-neplanocin F
title_fullStr Enantioselective synthesis of (+)-neplanocin F
title_full_unstemmed Enantioselective synthesis of (+)-neplanocin F
title_sort enantioselective synthesis of (+)-neplanocin f
publishDate 2002
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v58_n16_p3129_Comin
http://hdl.handle.net/20.500.12110/paper_00404020_v58_n16_p3129_Comin
work_keys_str_mv AT cominmariajulieta enantioselectivesynthesisofneplanocinf
AT rodriguezjuanbautista enantioselectivesynthesisofneplanocinf
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