Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus

A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with...

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Detalles Bibliográficos
Autores principales: Seldes, Alicia Marta, Maier, Marta Silvia
Publicado: 2001
Materias:
Antifungal activity
Glycosides
Holothuroidea
Psolus patagonicus
Triterpenes
antifungal agent
glycoside
patagonicoside a
triterpenic glycoside
unclassified drug
antifungal activity
article
carbon nuclear magnetic resonance
Cladosporium cucumerinum
controlled study
desulfurization
dose response
drug isolation
drug structure
echinoderm
mass spectrometry
nonhuman
priority journal
proton nuclear magnetic resonance
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v57_n47_p9563_Murray
http://hdl.handle.net/20.500.12110/paper_00404020_v57_n47_p9563_Murray
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_00404020_v57_n47_p9563_Murray
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spelling paper:paper_00404020_v57_n47_p9563_Murray2023-06-08T15:04:14Z Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus Seldes, Alicia Marta Maier, Marta Silvia Antifungal activity Glycosides Holothuroidea Psolus patagonicus Triterpenes antifungal agent glycoside patagonicoside a triterpenic glycoside unclassified drug antifungal activity article carbon nuclear magnetic resonance Cladosporium cucumerinum controlled study desulfurization dose response drug isolation drug structure echinoderm mass spectrometry nonhuman priority journal proton nuclear magnetic resonance A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifungal activity against the pathogenic fungus Cladosporium cucumerinum. © 2001 Elsevier Science Ltd. All rights reserved. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Maier, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2001 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v57_n47_p9563_Murray http://hdl.handle.net/20.500.12110/paper_00404020_v57_n47_p9563_Murray
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Antifungal activity
Glycosides
Holothuroidea
Psolus patagonicus
Triterpenes
antifungal agent
glycoside
patagonicoside a
triterpenic glycoside
unclassified drug
antifungal activity
article
carbon nuclear magnetic resonance
Cladosporium cucumerinum
controlled study
desulfurization
dose response
drug isolation
drug structure
echinoderm
mass spectrometry
nonhuman
priority journal
proton nuclear magnetic resonance
spellingShingle Antifungal activity
Glycosides
Holothuroidea
Psolus patagonicus
Triterpenes
antifungal agent
glycoside
patagonicoside a
triterpenic glycoside
unclassified drug
antifungal activity
article
carbon nuclear magnetic resonance
Cladosporium cucumerinum
controlled study
desulfurization
dose response
drug isolation
drug structure
echinoderm
mass spectrometry
nonhuman
priority journal
proton nuclear magnetic resonance
Seldes, Alicia Marta
Maier, Marta Silvia
Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
topic_facet Antifungal activity
Glycosides
Holothuroidea
Psolus patagonicus
Triterpenes
antifungal agent
glycoside
patagonicoside a
triterpenic glycoside
unclassified drug
antifungal activity
article
carbon nuclear magnetic resonance
Cladosporium cucumerinum
controlled study
desulfurization
dose response
drug isolation
drug structure
echinoderm
mass spectrometry
nonhuman
priority journal
proton nuclear magnetic resonance
description A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifungal activity against the pathogenic fungus Cladosporium cucumerinum. © 2001 Elsevier Science Ltd. All rights reserved.
author Seldes, Alicia Marta
Maier, Marta Silvia
author_facet Seldes, Alicia Marta
Maier, Marta Silvia
author_sort Seldes, Alicia Marta
title Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
title_short Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
title_full Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
title_fullStr Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
title_full_unstemmed Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
title_sort patagonicoside a: a novel antifungal disulfated triterpene glycoside from the sea cucumber psolus patagonicus
publishDate 2001
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v57_n47_p9563_Murray
http://hdl.handle.net/20.500.12110/paper_00404020_v57_n47_p9563_Murray
work_keys_str_mv AT seldesaliciamarta patagonicosideaanovelantifungaldisulfatedtriterpeneglycosidefromtheseacucumberpsoluspatagonicus
AT maiermartasilvia patagonicosideaanovelantifungaldisulfatedtriterpeneglycosidefromtheseacucumberpsoluspatagonicus
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