Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition
Novel 10-{[3-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)- 4,5-dihydro-5-isoxazolyl]methyl}-9(10H)-acridinone derivatives (13-16) were synthesized by 1,3-dipolar cycloaddition using the carbohydrate derivative as dipole and different 10-allyl-9(10H)-acridinone derivatives (9-12) as...
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2007
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00397911_v37_n23_p4209_Fascio http://hdl.handle.net/20.500.12110/paper_00397911_v37_n23_p4209_Fascio |
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paper:paper_00397911_v37_n23_p4209_Fascio2023-06-08T15:03:41Z Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition Fascio, Mirta Liliana D'Accorso, Norma Beatriz 1,3-dipolar cycloaddition Acridinones Carbohydrates Isoxazolines N-allylation 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 4 methoxy 9(10h) acridinone 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone 10 allyl 3 chloro 5 methoxy 9(10h) acridinone 10 allyl 3 chloro 9(10h) acridinone 10 allyl 4 methoxy 9(10h) acridinone 10 allyl 9(10h) acridinone 3 chloro 10 [[3 ( hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 6 methoxy 9(10h) acridinone 3 chloro 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone acridinone derivative carbohydrate derivative organic compound unclassified drug article cycloaddition drug activity drug determination drug structure drug synthesis spectroscopy structure analysis Novel 10-{[3-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)- 4,5-dihydro-5-isoxazolyl]methyl}-9(10H)-acridinone derivatives (13-16) were synthesized by 1,3-dipolar cycloaddition using the carbohydrate derivative as dipole and different 10-allyl-9(10H)-acridinone derivatives (9-12) as dipolarophiles. The new cycloadducts as well as the dipolarophiles precursors were characterized spectroscopically. Copyright © Taylor & Francis Group, LLC. Fil:Fascio, M.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:D'Accorso, N.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2007 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00397911_v37_n23_p4209_Fascio http://hdl.handle.net/20.500.12110/paper_00397911_v37_n23_p4209_Fascio |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
1,3-dipolar cycloaddition Acridinones Carbohydrates Isoxazolines N-allylation 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 4 methoxy 9(10h) acridinone 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone 10 allyl 3 chloro 5 methoxy 9(10h) acridinone 10 allyl 3 chloro 9(10h) acridinone 10 allyl 4 methoxy 9(10h) acridinone 10 allyl 9(10h) acridinone 3 chloro 10 [[3 ( hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 6 methoxy 9(10h) acridinone 3 chloro 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone acridinone derivative carbohydrate derivative organic compound unclassified drug article cycloaddition drug activity drug determination drug structure drug synthesis spectroscopy structure analysis |
| spellingShingle |
1,3-dipolar cycloaddition Acridinones Carbohydrates Isoxazolines N-allylation 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 4 methoxy 9(10h) acridinone 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone 10 allyl 3 chloro 5 methoxy 9(10h) acridinone 10 allyl 3 chloro 9(10h) acridinone 10 allyl 4 methoxy 9(10h) acridinone 10 allyl 9(10h) acridinone 3 chloro 10 [[3 ( hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 6 methoxy 9(10h) acridinone 3 chloro 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone acridinone derivative carbohydrate derivative organic compound unclassified drug article cycloaddition drug activity drug determination drug structure drug synthesis spectroscopy structure analysis Fascio, Mirta Liliana D'Accorso, Norma Beatriz Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| topic_facet |
1,3-dipolar cycloaddition Acridinones Carbohydrates Isoxazolines N-allylation 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 4 methoxy 9(10h) acridinone 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone 10 allyl 3 chloro 5 methoxy 9(10h) acridinone 10 allyl 3 chloro 9(10h) acridinone 10 allyl 4 methoxy 9(10h) acridinone 10 allyl 9(10h) acridinone 3 chloro 10 [[3 ( hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 6 methoxy 9(10h) acridinone 3 chloro 10 [[3 (6 hydroxy 2,2 dimethyltetrahydrofuro[2,3 d][1,3]dioxol 5 yl) 4,5 dihydro 5 isoxazolyl]methyl] 9(10h) acridinone acridinone derivative carbohydrate derivative organic compound unclassified drug article cycloaddition drug activity drug determination drug structure drug synthesis spectroscopy structure analysis |
| description |
Novel 10-{[3-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)- 4,5-dihydro-5-isoxazolyl]methyl}-9(10H)-acridinone derivatives (13-16) were synthesized by 1,3-dipolar cycloaddition using the carbohydrate derivative as dipole and different 10-allyl-9(10H)-acridinone derivatives (9-12) as dipolarophiles. The new cycloadducts as well as the dipolarophiles precursors were characterized spectroscopically. Copyright © Taylor & Francis Group, LLC. |
| author |
Fascio, Mirta Liliana D'Accorso, Norma Beatriz |
| author_facet |
Fascio, Mirta Liliana D'Accorso, Norma Beatriz |
| author_sort |
Fascio, Mirta Liliana |
| title |
Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| title_short |
Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| title_full |
Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| title_fullStr |
Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| title_full_unstemmed |
Synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| title_sort |
synthesis of novel carbohydrate acridinone derivatives with potential biological activities using 1,3-dipolar cycloaddition |
| publishDate |
2007 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00397911_v37_n23_p4209_Fascio http://hdl.handle.net/20.500.12110/paper_00397911_v37_n23_p4209_Fascio |
| work_keys_str_mv |
AT fasciomirtaliliana synthesisofnovelcarbohydrateacridinonederivativeswithpotentialbiologicalactivitiesusing13dipolarcycloaddition AT daccorsonormabeatriz synthesisofnovelcarbohydrateacridinonederivativeswithpotentialbiologicalactivitiesusing13dipolarcycloaddition |
| _version_ |
1768545592422694912 |