id paper:paper_00368075_v345_n6193_p222_Soroldoni
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spelling paper:paper_00368075_v345_n6193_p222_Soroldoni2023-06-08T15:02:08Z A doppler effect in embryonic pattern formation cyprinid Doppler effect embryo embryonic development genetic variation animal experiment article biological rhythm Doppler flowmetry embryo development embryo pattern formation embryo segmentation embryonic structures gene expression genetic analysis germ layer kinematics nonhuman oscillation physical parameters priority journal spike wave steady state tissue level transgenics zebra fish animal animal embryo genetics morphogenesis periodicity physiology prenatal development Animals Body Patterning Doppler Effect Embryo, Nonmammalian Periodicity Zebrafish During embryonic development, temporal and spatial cues are coordinated to generate a segmented body axis. In sequentially segmenting animals, the rhythm of segmentation is reported to be controlled by the time scale of genetic oscillations that periodically trigger new segment formation. However, we present real-time measurements of genetic oscillations in zebrafish embryos showing that their time scale is not sufficient to explain the temporal period of segmentation. A second time scale, the rate of tissue shortening, contributes to the period of segmentation through a Doppler effect. This contribution is modulated by a gradual change in the oscillation profile across the tissue. We conclude that the rhythm of segmentation is an emergent property controlled by the time scale of genetic oscillations, the change of oscillation profile, and tissue shortening. 2014 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00368075_v345_n6193_p222_Soroldoni http://hdl.handle.net/20.500.12110/paper_00368075_v345_n6193_p222_Soroldoni
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic cyprinid
Doppler effect
embryo
embryonic development
genetic variation
animal experiment
article
biological rhythm
Doppler flowmetry
embryo development
embryo pattern formation
embryo segmentation
embryonic structures
gene expression
genetic analysis
germ layer
kinematics
nonhuman
oscillation
physical parameters
priority journal
spike wave
steady state
tissue level
transgenics
zebra fish
animal
animal embryo
genetics
morphogenesis
periodicity
physiology
prenatal development
Animals
Body Patterning
Doppler Effect
Embryo, Nonmammalian
Periodicity
Zebrafish
spellingShingle cyprinid
Doppler effect
embryo
embryonic development
genetic variation
animal experiment
article
biological rhythm
Doppler flowmetry
embryo development
embryo pattern formation
embryo segmentation
embryonic structures
gene expression
genetic analysis
germ layer
kinematics
nonhuman
oscillation
physical parameters
priority journal
spike wave
steady state
tissue level
transgenics
zebra fish
animal
animal embryo
genetics
morphogenesis
periodicity
physiology
prenatal development
Animals
Body Patterning
Doppler Effect
Embryo, Nonmammalian
Periodicity
Zebrafish
A doppler effect in embryonic pattern formation
topic_facet cyprinid
Doppler effect
embryo
embryonic development
genetic variation
animal experiment
article
biological rhythm
Doppler flowmetry
embryo development
embryo pattern formation
embryo segmentation
embryonic structures
gene expression
genetic analysis
germ layer
kinematics
nonhuman
oscillation
physical parameters
priority journal
spike wave
steady state
tissue level
transgenics
zebra fish
animal
animal embryo
genetics
morphogenesis
periodicity
physiology
prenatal development
Animals
Body Patterning
Doppler Effect
Embryo, Nonmammalian
Periodicity
Zebrafish
description During embryonic development, temporal and spatial cues are coordinated to generate a segmented body axis. In sequentially segmenting animals, the rhythm of segmentation is reported to be controlled by the time scale of genetic oscillations that periodically trigger new segment formation. However, we present real-time measurements of genetic oscillations in zebrafish embryos showing that their time scale is not sufficient to explain the temporal period of segmentation. A second time scale, the rate of tissue shortening, contributes to the period of segmentation through a Doppler effect. This contribution is modulated by a gradual change in the oscillation profile across the tissue. We conclude that the rhythm of segmentation is an emergent property controlled by the time scale of genetic oscillations, the change of oscillation profile, and tissue shortening.
title A doppler effect in embryonic pattern formation
title_short A doppler effect in embryonic pattern formation
title_full A doppler effect in embryonic pattern formation
title_fullStr A doppler effect in embryonic pattern formation
title_full_unstemmed A doppler effect in embryonic pattern formation
title_sort doppler effect in embryonic pattern formation
publishDate 2014
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00368075_v345_n6193_p222_Soroldoni
http://hdl.handle.net/20.500.12110/paper_00368075_v345_n6193_p222_Soroldoni
_version_ 1768542402028503040