Biosynthesis of withanolides in Acnistus breviflorus. Incorporation of labelled 24-methylenecholesterol
Feeding experiments with [24-14C] 24-methylenecholesterol and mixtures of this sterol and [7-3H] 24-methylenecholesterol were performed to study the biosynthesis of withanolides in the plant Acnistus breviflorus. The results indicate that the side chain of the sterol precursor should be broken betwe...
Guardado en:
| Autores principales: | , , |
|---|---|
| Publicado: |
1994
|
| Materias: | |
| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v35_n4_p927_Monteagudo http://hdl.handle.net/20.500.12110/paper_00319422_v35_n4_p927_Monteagudo |
| Aporte de: |
| Sumario: | Feeding experiments with [24-14C] 24-methylenecholesterol and mixtures of this sterol and [7-3H] 24-methylenecholesterol were performed to study the biosynthesis of withanolides in the plant Acnistus breviflorus. The results indicate that the side chain of the sterol precursor should be broken between C-24 and C-25 to give an intermediate which follows the biogenetic pathway into withaferin A, jaborosalactone A and jaborosalactone D. © 1994. |
|---|