Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimula...
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1979
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky http://hdl.handle.net/20.500.12110/paper_00283835_v29_n3_p163_Moguilevsky |
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paper:paper_00283835_v29_n3_p163_Moguilevsky2023-06-08T14:54:58Z Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats LH release Pineal gland Melatonin Superior cervical ganglion estradiol melatonin progesterone animal experiment castration dose response drug response luteinizing hormone release ovariectomy rat superior cervical ganglionectomy Animal Castration Estradiol Female Ganglia, Sympathetic Luteinizing Hormone Melatonin Progesterone Rats The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimulatory and the highest (250 μg/IOO g body weight) inhibitory. Superior cervical ganglionectomy negated the inhibitory effect of the high melatonin dose on steroid-induced LH release. Rather melatonin injection to ganglionectomized rats resulted in significantly higher serum LH values than those of animals injected with estradiol and progesterone alone. Melatonin treatment failed to modify postcastration serum LH levels. © 1979 S. Karger AG, Basel. 1979 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky http://hdl.handle.net/20.500.12110/paper_00283835_v29_n3_p163_Moguilevsky |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
LH release Pineal gland Melatonin Superior cervical ganglion estradiol melatonin progesterone animal experiment castration dose response drug response luteinizing hormone release ovariectomy rat superior cervical ganglionectomy Animal Castration Estradiol Female Ganglia, Sympathetic Luteinizing Hormone Melatonin Progesterone Rats |
spellingShingle |
LH release Pineal gland Melatonin Superior cervical ganglion estradiol melatonin progesterone animal experiment castration dose response drug response luteinizing hormone release ovariectomy rat superior cervical ganglionectomy Animal Castration Estradiol Female Ganglia, Sympathetic Luteinizing Hormone Melatonin Progesterone Rats Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
topic_facet |
LH release Pineal gland Melatonin Superior cervical ganglion estradiol melatonin progesterone animal experiment castration dose response drug response luteinizing hormone release ovariectomy rat superior cervical ganglionectomy Animal Castration Estradiol Female Ganglia, Sympathetic Luteinizing Hormone Melatonin Progesterone Rats |
description |
The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimulatory and the highest (250 μg/IOO g body weight) inhibitory. Superior cervical ganglionectomy negated the inhibitory effect of the high melatonin dose on steroid-induced LH release. Rather melatonin injection to ganglionectomized rats resulted in significantly higher serum LH values than those of animals injected with estradiol and progesterone alone. Melatonin treatment failed to modify postcastration serum LH levels. © 1979 S. Karger AG, Basel. |
title |
Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
title_short |
Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
title_full |
Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
title_fullStr |
Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
title_full_unstemmed |
Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
title_sort |
effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats |
publishDate |
1979 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky http://hdl.handle.net/20.500.12110/paper_00283835_v29_n3_p163_Moguilevsky |
_version_ |
1768546433169883136 |