Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats

The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimula...

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Detalles Bibliográficos
Publicado: 1979
Materias:
rat
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky
http://hdl.handle.net/20.500.12110/paper_00283835_v29_n3_p163_Moguilevsky
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id paper:paper_00283835_v29_n3_p163_Moguilevsky
record_format dspace
spelling paper:paper_00283835_v29_n3_p163_Moguilevsky2023-06-08T14:54:58Z Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats LH release Pineal gland Melatonin Superior cervical ganglion estradiol melatonin progesterone animal experiment castration dose response drug response luteinizing hormone release ovariectomy rat superior cervical ganglionectomy Animal Castration Estradiol Female Ganglia, Sympathetic Luteinizing Hormone Melatonin Progesterone Rats The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimulatory and the highest (250 μg/IOO g body weight) inhibitory. Superior cervical ganglionectomy negated the inhibitory effect of the high melatonin dose on steroid-induced LH release. Rather melatonin injection to ganglionectomized rats resulted in significantly higher serum LH values than those of animals injected with estradiol and progesterone alone. Melatonin treatment failed to modify postcastration serum LH levels. © 1979 S. Karger AG, Basel. 1979 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky http://hdl.handle.net/20.500.12110/paper_00283835_v29_n3_p163_Moguilevsky
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic LH release
Pineal gland Melatonin
Superior cervical ganglion
estradiol
melatonin
progesterone
animal experiment
castration
dose response
drug response
luteinizing hormone release
ovariectomy
rat
superior cervical ganglionectomy
Animal
Castration
Estradiol
Female
Ganglia, Sympathetic
Luteinizing Hormone
Melatonin
Progesterone
Rats
spellingShingle LH release
Pineal gland Melatonin
Superior cervical ganglion
estradiol
melatonin
progesterone
animal experiment
castration
dose response
drug response
luteinizing hormone release
ovariectomy
rat
superior cervical ganglionectomy
Animal
Castration
Estradiol
Female
Ganglia, Sympathetic
Luteinizing Hormone
Melatonin
Progesterone
Rats
Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
topic_facet LH release
Pineal gland Melatonin
Superior cervical ganglion
estradiol
melatonin
progesterone
animal experiment
castration
dose response
drug response
luteinizing hormone release
ovariectomy
rat
superior cervical ganglionectomy
Animal
Castration
Estradiol
Female
Ganglia, Sympathetic
Luteinizing Hormone
Melatonin
Progesterone
Rats
description The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimulatory and the highest (250 μg/IOO g body weight) inhibitory. Superior cervical ganglionectomy negated the inhibitory effect of the high melatonin dose on steroid-induced LH release. Rather melatonin injection to ganglionectomized rats resulted in significantly higher serum LH values than those of animals injected with estradiol and progesterone alone. Melatonin treatment failed to modify postcastration serum LH levels. © 1979 S. Karger AG, Basel.
title Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
title_short Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
title_full Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
title_fullStr Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
title_full_unstemmed Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
title_sort effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
publishDate 1979
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky
http://hdl.handle.net/20.500.12110/paper_00283835_v29_n3_p163_Moguilevsky
_version_ 1768546433169883136