Phantom percepts: Tinnitus and pain as persisting aversive memory networks
Phantomperception refers to the conscious awareness of a percept in the absence of an external stimulus. On the basis of basic neuroscience on perception and clinical research in phantom pain and phantom sound, we propose a working model for their origin. Sensory deafferentation results in high-freq...
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2011
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paper:paper_00278424_v108_n20_p8075_DeRidder2023-06-08T14:54:24Z Phantom percepts: Tinnitus and pain as persisting aversive memory networks amygdaloid nucleus anterior cingulate awareness deafferentation distress syndrome gamma rhythm human insula learning memory nonhuman perception phantom pain phantom perception priority journal reinforcement review sensory cortex tinnitus Awareness Consciousness Humans Memory Models, Neurological Nerve Net Pain Perceptual Disorders Tinnitus Phantomperception refers to the conscious awareness of a percept in the absence of an external stimulus. On the basis of basic neuroscience on perception and clinical research in phantom pain and phantom sound, we propose a working model for their origin. Sensory deafferentation results in high-frequency, gamma band, synchronized neuronal activity in the sensory cortex. This activity becomes a conscious percept only if it is connected to larger coactivated "(self-)awareness" and "salience" brain networks. Through the involvement of learning mechanisms, the phantom percept becomes associated to distress, which in turn is reflected by a simultaneously coactivated nonspecific distress network consisting of the anterior cingulate cortex, anterior insula, and amygdala. Memory mechanisms play a role in the persistence of the awareness of the phantom percept, as well as in the reinforcement of the associated distress. Thus, different dynamic overlapping brain networks should be considered as targets for the treatment of this disorder. 2011 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00278424_v108_n20_p8075_DeRidder http://hdl.handle.net/20.500.12110/paper_00278424_v108_n20_p8075_DeRidder |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
amygdaloid nucleus anterior cingulate awareness deafferentation distress syndrome gamma rhythm human insula learning memory nonhuman perception phantom pain phantom perception priority journal reinforcement review sensory cortex tinnitus Awareness Consciousness Humans Memory Models, Neurological Nerve Net Pain Perceptual Disorders Tinnitus |
| spellingShingle |
amygdaloid nucleus anterior cingulate awareness deafferentation distress syndrome gamma rhythm human insula learning memory nonhuman perception phantom pain phantom perception priority journal reinforcement review sensory cortex tinnitus Awareness Consciousness Humans Memory Models, Neurological Nerve Net Pain Perceptual Disorders Tinnitus Phantom percepts: Tinnitus and pain as persisting aversive memory networks |
| topic_facet |
amygdaloid nucleus anterior cingulate awareness deafferentation distress syndrome gamma rhythm human insula learning memory nonhuman perception phantom pain phantom perception priority journal reinforcement review sensory cortex tinnitus Awareness Consciousness Humans Memory Models, Neurological Nerve Net Pain Perceptual Disorders Tinnitus |
| description |
Phantomperception refers to the conscious awareness of a percept in the absence of an external stimulus. On the basis of basic neuroscience on perception and clinical research in phantom pain and phantom sound, we propose a working model for their origin. Sensory deafferentation results in high-frequency, gamma band, synchronized neuronal activity in the sensory cortex. This activity becomes a conscious percept only if it is connected to larger coactivated "(self-)awareness" and "salience" brain networks. Through the involvement of learning mechanisms, the phantom percept becomes associated to distress, which in turn is reflected by a simultaneously coactivated nonspecific distress network consisting of the anterior cingulate cortex, anterior insula, and amygdala. Memory mechanisms play a role in the persistence of the awareness of the phantom percept, as well as in the reinforcement of the associated distress. Thus, different dynamic overlapping brain networks should be considered as targets for the treatment of this disorder. |
| title |
Phantom percepts: Tinnitus and pain as persisting aversive memory networks |
| title_short |
Phantom percepts: Tinnitus and pain as persisting aversive memory networks |
| title_full |
Phantom percepts: Tinnitus and pain as persisting aversive memory networks |
| title_fullStr |
Phantom percepts: Tinnitus and pain as persisting aversive memory networks |
| title_full_unstemmed |
Phantom percepts: Tinnitus and pain as persisting aversive memory networks |
| title_sort |
phantom percepts: tinnitus and pain as persisting aversive memory networks |
| publishDate |
2011 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00278424_v108_n20_p8075_DeRidder http://hdl.handle.net/20.500.12110/paper_00278424_v108_n20_p8075_DeRidder |
| _version_ |
1768542928805822464 |