Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons
In the isolated rat tail artery preloaded with 3H-noradrenaline, neither acetylsalicyclic acid nor indomethacin modified the tritium release evoked by the Black Widow spider venom gland extract (BWGE), whereas clonidine diminished this effect of the venom. The data suggest that the BWGE process may...
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1980
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00243205_v26_n21_p1761_FernandezPardal http://hdl.handle.net/20.500.12110/paper_00243205_v26_n21_p1761_FernandezPardal |
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paper:paper_00243205_v26_n21_p1761_FernandezPardal |
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paper:paper_00243205_v26_n21_p1761_FernandezPardal2025-07-30T17:33:39Z Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons acetylsalicylic acid clonidine indometacin noradrenalin prostaglandin radioisotope spider venom animal experiment autonomic nervous system drug release in vitro study noradrenalin h 3 peripheral vascular system rat sympathetic nerve tail artery Animal Arthropod Venoms Aspirin Black Widow Spider Catecholamines Clonidine In Vitro Indomethacin Male Muscle, Smooth, Vascular Neurons Norepinephrine Potassium Prostaglandins Rats Spider Venoms Sympathetic Nervous System In the isolated rat tail artery preloaded with 3H-noradrenaline, neither acetylsalicyclic acid nor indomethacin modified the tritium release evoked by the Black Widow spider venom gland extract (BWGE), whereas clonidine diminished this effect of the venom. The data suggest that the BWGE process may operate in parallel with the prostaglandin mechanism and in series with the NA-mediated feed back pathway. It can not be excluded a prostaglandin interaction on the release process at a step prior to the point at which the venom acts. © 1980. 1980 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00243205_v26_n21_p1761_FernandezPardal http://hdl.handle.net/20.500.12110/paper_00243205_v26_n21_p1761_FernandezPardal |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
acetylsalicylic acid clonidine indometacin noradrenalin prostaglandin radioisotope spider venom animal experiment autonomic nervous system drug release in vitro study noradrenalin h 3 peripheral vascular system rat sympathetic nerve tail artery Animal Arthropod Venoms Aspirin Black Widow Spider Catecholamines Clonidine In Vitro Indomethacin Male Muscle, Smooth, Vascular Neurons Norepinephrine Potassium Prostaglandins Rats Spider Venoms Sympathetic Nervous System |
| spellingShingle |
acetylsalicylic acid clonidine indometacin noradrenalin prostaglandin radioisotope spider venom animal experiment autonomic nervous system drug release in vitro study noradrenalin h 3 peripheral vascular system rat sympathetic nerve tail artery Animal Arthropod Venoms Aspirin Black Widow Spider Catecholamines Clonidine In Vitro Indomethacin Male Muscle, Smooth, Vascular Neurons Norepinephrine Potassium Prostaglandins Rats Spider Venoms Sympathetic Nervous System Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| topic_facet |
acetylsalicylic acid clonidine indometacin noradrenalin prostaglandin radioisotope spider venom animal experiment autonomic nervous system drug release in vitro study noradrenalin h 3 peripheral vascular system rat sympathetic nerve tail artery Animal Arthropod Venoms Aspirin Black Widow Spider Catecholamines Clonidine In Vitro Indomethacin Male Muscle, Smooth, Vascular Neurons Norepinephrine Potassium Prostaglandins Rats Spider Venoms Sympathetic Nervous System |
| description |
In the isolated rat tail artery preloaded with 3H-noradrenaline, neither acetylsalicyclic acid nor indomethacin modified the tritium release evoked by the Black Widow spider venom gland extract (BWGE), whereas clonidine diminished this effect of the venom. The data suggest that the BWGE process may operate in parallel with the prostaglandin mechanism and in series with the NA-mediated feed back pathway. It can not be excluded a prostaglandin interaction on the release process at a step prior to the point at which the venom acts. © 1980. |
| title |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| title_short |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| title_full |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| title_fullStr |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| title_full_unstemmed |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| title_sort |
inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons |
| publishDate |
1980 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00243205_v26_n21_p1761_FernandezPardal http://hdl.handle.net/20.500.12110/paper_00243205_v26_n21_p1761_FernandezPardal |
| _version_ |
1840320753536335872 |