ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene

The rate constants and thermodynamic parameters for the reaction of nine 6-R-2-nitrochlorobenzenes with piperidine in benzene have been determined. The reactions follow the Hammett relationship log (kR/kH) = σρ if the "bulky" substituents, bromine and methyl, are excluded. An approximate v...

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Publicado: 1965
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00223263_v30_n10_p3365_Sbarbati
http://hdl.handle.net/20.500.12110/paper_00223263_v30_n10_p3365_Sbarbati
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_00223263_v30_n10_p3365_Sbarbati
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spelling paper:paper_00223263_v30_n10_p3365_Sbarbati2025-07-30T17:31:23Z ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene The rate constants and thermodynamic parameters for the reaction of nine 6-R-2-nitrochlorobenzenes with piperidine in benzene have been determined. The reactions follow the Hammett relationship log (kR/kH) = σρ if the "bulky" substituents, bromine and methyl, are excluded. An approximate van der Waals radius of 1.9 Å. is proposed as the lower limit below which steric effects are negligible, and differences in rate are mainly determined by polar effects. The substituent influence on both enthalpy and entropy of activation is discussed. © 1965, American Chemical Society. All rights reserved. 1965 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00223263_v30_n10_p3365_Sbarbati http://hdl.handle.net/20.500.12110/paper_00223263_v30_n10_p3365_Sbarbati
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description The rate constants and thermodynamic parameters for the reaction of nine 6-R-2-nitrochlorobenzenes with piperidine in benzene have been determined. The reactions follow the Hammett relationship log (kR/kH) = σρ if the "bulky" substituents, bromine and methyl, are excluded. An approximate van der Waals radius of 1.9 Å. is proposed as the lower limit below which steric effects are negligible, and differences in rate are mainly determined by polar effects. The substituent influence on both enthalpy and entropy of activation is discussed. © 1965, American Chemical Society. All rights reserved.
title ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene
spellingShingle ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene
title_short ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene
title_full ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene
title_fullStr ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene
title_full_unstemmed ortho Effects on Nucleophilic Aromatic Substitution. The Reactions of 6-R-2-Nitrochlorobenzenes with Piperidine in Benzene
title_sort ortho effects on nucleophilic aromatic substitution. the reactions of 6-r-2-nitrochlorobenzenes with piperidine in benzene
publishDate 1965
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00223263_v30_n10_p3365_Sbarbati
http://hdl.handle.net/20.500.12110/paper_00223263_v30_n10_p3365_Sbarbati
_version_ 1840325922366947328

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