Synthesis and antiviral evaluation of some carbonucleoside analogues
1,2-O-Isopropylidene-α-L-threofuranosyl heterocyclic derivatives were synthesized from 1,2-O-isopropylidene-α-D-xilopentadialdo-1,4-furanose and tested for antiviral activity against herpes simplex virus type 1, dengue virus type 2 and Junín virus. For comparative propose, the antiviral activity of...
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2005
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho http://hdl.handle.net/20.500.12110/paper_0022152X_v42_n5_p979_MartinsAlho |
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paper:paper_0022152X_v42_n5_p979_MartinsAlho2023-06-08T14:46:50Z Synthesis and antiviral evaluation of some carbonucleoside analogues 1,2 o isopropylidene alpha dextro xylopentadialdo 1,4 furanose 1,2 o isopropylidene alpha levo furanosyl derivative antivirus agent carbonucleoside derivative heterocyclic compound nucleoside derivative pyranosyl derivative unclassified drug antiviral activity article Dengue virus drug synthesis Herpes simplex virus 1 Junin virus nonhuman 1,2-O-Isopropylidene-α-L-threofuranosyl heterocyclic derivatives were synthesized from 1,2-O-isopropylidene-α-D-xilopentadialdo-1,4-furanose and tested for antiviral activity against herpes simplex virus type 1, dengue virus type 2 and Junín virus. For comparative propose, the antiviral activity of some of their pyranosyl analogues were also tested. The furanosyl derivatives showed to be moderate inhibitors of Junin virus and, in general, proved to be more effective than the pyranosyl analogues. 2005 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho http://hdl.handle.net/20.500.12110/paper_0022152X_v42_n5_p979_MartinsAlho |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
1,2 o isopropylidene alpha dextro xylopentadialdo 1,4 furanose 1,2 o isopropylidene alpha levo furanosyl derivative antivirus agent carbonucleoside derivative heterocyclic compound nucleoside derivative pyranosyl derivative unclassified drug antiviral activity article Dengue virus drug synthesis Herpes simplex virus 1 Junin virus nonhuman |
| spellingShingle |
1,2 o isopropylidene alpha dextro xylopentadialdo 1,4 furanose 1,2 o isopropylidene alpha levo furanosyl derivative antivirus agent carbonucleoside derivative heterocyclic compound nucleoside derivative pyranosyl derivative unclassified drug antiviral activity article Dengue virus drug synthesis Herpes simplex virus 1 Junin virus nonhuman Synthesis and antiviral evaluation of some carbonucleoside analogues |
| topic_facet |
1,2 o isopropylidene alpha dextro xylopentadialdo 1,4 furanose 1,2 o isopropylidene alpha levo furanosyl derivative antivirus agent carbonucleoside derivative heterocyclic compound nucleoside derivative pyranosyl derivative unclassified drug antiviral activity article Dengue virus drug synthesis Herpes simplex virus 1 Junin virus nonhuman |
| description |
1,2-O-Isopropylidene-α-L-threofuranosyl heterocyclic derivatives were synthesized from 1,2-O-isopropylidene-α-D-xilopentadialdo-1,4-furanose and tested for antiviral activity against herpes simplex virus type 1, dengue virus type 2 and Junín virus. For comparative propose, the antiviral activity of some of their pyranosyl analogues were also tested. The furanosyl derivatives showed to be moderate inhibitors of Junin virus and, in general, proved to be more effective than the pyranosyl analogues. |
| title |
Synthesis and antiviral evaluation of some carbonucleoside analogues |
| title_short |
Synthesis and antiviral evaluation of some carbonucleoside analogues |
| title_full |
Synthesis and antiviral evaluation of some carbonucleoside analogues |
| title_fullStr |
Synthesis and antiviral evaluation of some carbonucleoside analogues |
| title_full_unstemmed |
Synthesis and antiviral evaluation of some carbonucleoside analogues |
| title_sort |
synthesis and antiviral evaluation of some carbonucleoside analogues |
| publishDate |
2005 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho http://hdl.handle.net/20.500.12110/paper_0022152X_v42_n5_p979_MartinsAlho |
| _version_ |
1768543787202641920 |