Early cell cycle diacylglycerol (DAG) content and protein kinase C (PKC) activity enhancement potentiates prostaglandin F2α (PGF2α) induced mitogenesis in Swiss 3T3 cells

R59022, a diacylglycerol kinase inhibitor, enhances the prostaglandin F2α (PGF2α)-induced diacylglycerol (DAG) synthesis in Swiss 3T3 cells. It also potentiates the PGF2α-mediated protein kinase C (PKC)-dependent 80 kDa protein (80K) phosphorylation and initiation of DNA replication. R 59022 enhance...

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Detalles Bibliográficos
Publicado:	1993
Materias:	Diacylglycerol kinase DNA synthesis Prostaglandin F2α Protein kinase C R 59022 6 [2 [4 [(4 fluorophenyl)phenylmethylene] 1 piperidyl]ethyl] 7 methyl 5h thiazolo[3,2 a]pyrimidin 5 one diacylglycerol insulin prostaglandin f2 alpha protein kinase c animal cell article cell cycle mitogenesis mouse nonhuman priority journal 3T3 Cells Animal Cell Cycle Cell Division Diacylglycerol Kinase Diglycerides Dinoprost DNA Replication Insulin Mice Phosphorylation Phosphotransferases Protein Kinase C Pyrimidinones Support, Non-U.S. Gov't Thiazoles
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00145793_v316_n1_p68_Goin http://hdl.handle.net/20.500.12110/paper_00145793_v316_n1_p68_Goin
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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