Neurospora crassa cDNA clones coding for a new member of the ras protein family

A new member of the ras gene family was characterized from Neurospora crassa cDNA libraries. The clone designated NC-ras codes for a polypeptide containing 213 amino acids (Mr 24000). This polypeptide is 84% homologous to the H-ras-1 domain comprising the first 80 amino acids and 60% homologous to t...

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Autores principales: Altschuler, Daniel Leonardo, Muro, Andrés Fernando, Schijman, Alejandro Gabriel, Torres, Héctor Norberto
Publicado: 1990
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00145793_v273_n1-2_p103_Altschuler
http://hdl.handle.net/20.500.12110/paper_00145793_v273_n1-2_p103_Altschuler
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spelling paper:paper_00145793_v273_n1-2_p103_Altschuler2023-06-08T14:37:34Z Neurospora crassa cDNA clones coding for a new member of the ras protein family Altschuler, Daniel Leonardo Muro, Andrés Fernando Schijman, Alejandro Gabriel Torres, Héctor Norberto cDNA Neurospora crassa ras-sequence complementary dna ras protein article dna sequence fungus neurospora crassa nonhuman priority journal Amino Acid Sequence Animal Base Sequence Cloning, Molecular Comparative Study DNA Probes DNA, Fungal Fungal Proteins Gene Library Genes, ras Human Molecular Sequence Data Multigene Family Neurospora crassa Rats RNA, Fungal Sequence Homology, Nucleic Acid Support, Non-U.S. Gov't Fungi Neurospora crassa A new member of the ras gene family was characterized from Neurospora crassa cDNA libraries. The clone designated NC-ras codes for a polypeptide containing 213 amino acids (Mr 24000). This polypeptide is 84% homologous to the H-ras-1 domain comprising the first 80 amino acids and 60% homologous to the next 84 residues. The NC-ras polypeptide contains all the well-known sequences involved in the interaction with GTP/GDP, the recognition of the Y13-259 neutralizing antibody, the 'effector site' for interaction with GAP proteins, and the CAAX acylation motif in the COOH-terminal. © 1990. Fil:Altschuler, D.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Muro, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Schijman, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Torres, H.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1990 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00145793_v273_n1-2_p103_Altschuler http://hdl.handle.net/20.500.12110/paper_00145793_v273_n1-2_p103_Altschuler
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic cDNA
Neurospora crassa
ras-sequence
complementary dna
ras protein
article
dna sequence
fungus
neurospora crassa
nonhuman
priority journal
Amino Acid Sequence
Animal
Base Sequence
Cloning, Molecular
Comparative Study
DNA Probes
DNA, Fungal
Fungal Proteins
Gene Library
Genes, ras
Human
Molecular Sequence Data
Multigene Family
Neurospora crassa
Rats
RNA, Fungal
Sequence Homology, Nucleic Acid
Support, Non-U.S. Gov't
Fungi
Neurospora crassa
spellingShingle cDNA
Neurospora crassa
ras-sequence
complementary dna
ras protein
article
dna sequence
fungus
neurospora crassa
nonhuman
priority journal
Amino Acid Sequence
Animal
Base Sequence
Cloning, Molecular
Comparative Study
DNA Probes
DNA, Fungal
Fungal Proteins
Gene Library
Genes, ras
Human
Molecular Sequence Data
Multigene Family
Neurospora crassa
Rats
RNA, Fungal
Sequence Homology, Nucleic Acid
Support, Non-U.S. Gov't
Fungi
Neurospora crassa
Altschuler, Daniel Leonardo
Muro, Andrés Fernando
Schijman, Alejandro Gabriel
Torres, Héctor Norberto
Neurospora crassa cDNA clones coding for a new member of the ras protein family
topic_facet cDNA
Neurospora crassa
ras-sequence
complementary dna
ras protein
article
dna sequence
fungus
neurospora crassa
nonhuman
priority journal
Amino Acid Sequence
Animal
Base Sequence
Cloning, Molecular
Comparative Study
DNA Probes
DNA, Fungal
Fungal Proteins
Gene Library
Genes, ras
Human
Molecular Sequence Data
Multigene Family
Neurospora crassa
Rats
RNA, Fungal
Sequence Homology, Nucleic Acid
Support, Non-U.S. Gov't
Fungi
Neurospora crassa
description A new member of the ras gene family was characterized from Neurospora crassa cDNA libraries. The clone designated NC-ras codes for a polypeptide containing 213 amino acids (Mr 24000). This polypeptide is 84% homologous to the H-ras-1 domain comprising the first 80 amino acids and 60% homologous to the next 84 residues. The NC-ras polypeptide contains all the well-known sequences involved in the interaction with GTP/GDP, the recognition of the Y13-259 neutralizing antibody, the 'effector site' for interaction with GAP proteins, and the CAAX acylation motif in the COOH-terminal. © 1990.
author Altschuler, Daniel Leonardo
Muro, Andrés Fernando
Schijman, Alejandro Gabriel
Torres, Héctor Norberto
author_facet Altschuler, Daniel Leonardo
Muro, Andrés Fernando
Schijman, Alejandro Gabriel
Torres, Héctor Norberto
author_sort Altschuler, Daniel Leonardo
title Neurospora crassa cDNA clones coding for a new member of the ras protein family
title_short Neurospora crassa cDNA clones coding for a new member of the ras protein family
title_full Neurospora crassa cDNA clones coding for a new member of the ras protein family
title_fullStr Neurospora crassa cDNA clones coding for a new member of the ras protein family
title_full_unstemmed Neurospora crassa cDNA clones coding for a new member of the ras protein family
title_sort neurospora crassa cdna clones coding for a new member of the ras protein family
publishDate 1990
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00145793_v273_n1-2_p103_Altschuler
http://hdl.handle.net/20.500.12110/paper_00145793_v273_n1-2_p103_Altschuler
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AT schijmanalejandrogabriel neurosporacrassacdnaclonescodingforanewmemberoftherasproteinfamily
AT torreshectornorberto neurosporacrassacdnaclonescodingforanewmemberoftherasproteinfamily
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