Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse

In human diabetes, degenerative and functional disorders of the central nervous system, including depression, are common findings. Defective dentate gyrus (DG) neurogenesis is associated with affective-related disorders and depression. We previously demonstrated reduced DG neurogenesis in a pharmaco...

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Guardado en:
Detalles Bibliográficos
Publicado: 2008
Materias:
BrdU
Dentate gyrus neurogenesis
GFAP
NeuN
NOD mouse
Type 1 diabetes mellitus
broxuridine
corticosterone
DNA
streptozocin
animal cell
animal experiment
animal model
animal tissue
article
autoimmunity
cell proliferation
cell survival
central nervous system disease
central nervous system function
confocal microscopy
controlled study
dentate gyrus
depression
female
hippocampus
hypophysis adrenal system
inflammation
insulin dependent diabetes mellitus
mood disorder
mouse
nonhuman
nonobese diabetic mouse
phenotype
priority journal
streptozocin diabetes
Age Factors
Analysis of Variance
Animals
Bromodeoxyuridine
Cell Count
Cell Proliferation
Corticosterone
Diabetes Mellitus, Type 1
Disease Models, Animal
Female
Glial Fibrillary Acidic Protein
Hippocampus
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Inbred NOD
Neurons
Phosphopyruvate Hydratase
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144886_v210_n2_p359_Beauquis
http://hdl.handle.net/20.500.12110/paper_00144886_v210_n2_p359_Beauquis
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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