Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat?
59Fe was incorporated in vivo into intestinal sacs prepared in iron deficient rats and 59Fe counts were detected in blood, spleen, liver, femur and intestine. The i.v. injection of isoproterenol (i.v. 2 μg/rat) or N′,O′-dibutyryladenosine 3′,5′-cyclic monophosphate (10 μM/100 g b.w.) enhanced signif...
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1984
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v100_n3-4_p369_Gutnisky http://hdl.handle.net/20.500.12110/paper_00142999_v100_n3-4_p369_Gutnisky |
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paper:paper_00142999_v100_n3-4_p369_Gutnisky |
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paper:paper_00142999_v100_n3-4_p369_Gutnisky2023-06-08T14:36:48Z Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? 5′-cyclic monophosphate Adrenoreceptors Iron absorption Iron distribution Isoproterenol N′ O′-Dibutyryladenosine 3′ Propranolol beta adrenergic receptor bucladesine iron iron 59 isoprenaline propranolol radioisotope animal experiment digestive system drug absorption drug distribution intestine absorption intestine mucosa nonhuman oral drug administration rat small intestine tissue distribution Animal Bucladesine Intestinal Absorption Iron Iron Radioisotopes Isoproterenol Male Propranolol Rats Rats, Inbred Strains Receptors, Adrenergic, beta Support, Non-U.S. Gov't Tissue Distribution 59Fe was incorporated in vivo into intestinal sacs prepared in iron deficient rats and 59Fe counts were detected in blood, spleen, liver, femur and intestine. The i.v. injection of isoproterenol (i.v. 2 μg/rat) or N′,O′-dibutyryladenosine 3′,5′-cyclic monophosphate (10 μM/100 g b.w.) enhanced significantly the iron counts in blood, spleen, liver and femur but not in intestine. (-)-Propranolol (2 mg · kg-1 b.w.i.v.) antagonized the stimulatory effect of isoproterenol. It is suggested that isoproterenol increases iron absorption via the stimulation of β-adrenoreceptors of the intestinal mucosa. © 1984. 1984 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v100_n3-4_p369_Gutnisky http://hdl.handle.net/20.500.12110/paper_00142999_v100_n3-4_p369_Gutnisky |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
5′-cyclic monophosphate Adrenoreceptors Iron absorption Iron distribution Isoproterenol N′ O′-Dibutyryladenosine 3′ Propranolol beta adrenergic receptor bucladesine iron iron 59 isoprenaline propranolol radioisotope animal experiment digestive system drug absorption drug distribution intestine absorption intestine mucosa nonhuman oral drug administration rat small intestine tissue distribution Animal Bucladesine Intestinal Absorption Iron Iron Radioisotopes Isoproterenol Male Propranolol Rats Rats, Inbred Strains Receptors, Adrenergic, beta Support, Non-U.S. Gov't Tissue Distribution |
| spellingShingle |
5′-cyclic monophosphate Adrenoreceptors Iron absorption Iron distribution Isoproterenol N′ O′-Dibutyryladenosine 3′ Propranolol beta adrenergic receptor bucladesine iron iron 59 isoprenaline propranolol radioisotope animal experiment digestive system drug absorption drug distribution intestine absorption intestine mucosa nonhuman oral drug administration rat small intestine tissue distribution Animal Bucladesine Intestinal Absorption Iron Iron Radioisotopes Isoproterenol Male Propranolol Rats Rats, Inbred Strains Receptors, Adrenergic, beta Support, Non-U.S. Gov't Tissue Distribution Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| topic_facet |
5′-cyclic monophosphate Adrenoreceptors Iron absorption Iron distribution Isoproterenol N′ O′-Dibutyryladenosine 3′ Propranolol beta adrenergic receptor bucladesine iron iron 59 isoprenaline propranolol radioisotope animal experiment digestive system drug absorption drug distribution intestine absorption intestine mucosa nonhuman oral drug administration rat small intestine tissue distribution Animal Bucladesine Intestinal Absorption Iron Iron Radioisotopes Isoproterenol Male Propranolol Rats Rats, Inbred Strains Receptors, Adrenergic, beta Support, Non-U.S. Gov't Tissue Distribution |
| description |
59Fe was incorporated in vivo into intestinal sacs prepared in iron deficient rats and 59Fe counts were detected in blood, spleen, liver, femur and intestine. The i.v. injection of isoproterenol (i.v. 2 μg/rat) or N′,O′-dibutyryladenosine 3′,5′-cyclic monophosphate (10 μM/100 g b.w.) enhanced significantly the iron counts in blood, spleen, liver and femur but not in intestine. (-)-Propranolol (2 mg · kg-1 b.w.i.v.) antagonized the stimulatory effect of isoproterenol. It is suggested that isoproterenol increases iron absorption via the stimulation of β-adrenoreceptors of the intestinal mucosa. © 1984. |
| title |
Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| title_short |
Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| title_full |
Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| title_fullStr |
Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| title_full_unstemmed |
Are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| title_sort |
are β-adrenoreceptors involved in the intestinal absorption and tissue distribution of iron in the rat? |
| publishDate |
1984 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v100_n3-4_p369_Gutnisky http://hdl.handle.net/20.500.12110/paper_00142999_v100_n3-4_p369_Gutnisky |
| _version_ |
1768541780786020352 |