Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin
The electrochemical behavior of mangiferin (MGN), a natural antioxidant compound, is examined using cyclic and differential pulse voltammetry in a protic medium on a glassy carbon electrode. The voltammograms exhibit a single irreversible pH-dependent anodic wave with current controlled by adsorptio...
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2010
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00134686_v56_n2_p797_Ferreira http://hdl.handle.net/20.500.12110/paper_00134686_v56_n2_p797_Ferreira |
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paper:paper_00134686_v56_n2_p797_Ferreira2023-06-08T14:35:58Z Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin β-Cyclodextrin Apparent formation constant Carbon-nanotube modified electrodes Mangiferin PM IRRAS Anodic waves Association constant Benesi-Hildebrand Cd complex Current-controlled Differential pulse voltammetry Direct method Electrochemical behaviors Electrochemical experiments Electrochemical investigations ELectrochemical methods Formation constants Glassy carbon electrodes Gold electrodes Host guest interactions Langmuir isotherm Lower detection limit Mangiferin Modified electrodes Natural antioxidants PH-dependent PM-IRRAS UV-vis spectroscopy Voltammograms Adsorption Carbon nanotubes Complexation Drug interactions Electrodes Glass membrane electrodes Glassy carbon Gold compounds Self assembled monolayers Ultraviolet spectroscopy Cyclic voltammetry The electrochemical behavior of mangiferin (MGN), a natural antioxidant compound, is examined using cyclic and differential pulse voltammetry in a protic medium on a glassy carbon electrode. The voltammograms exhibit a single irreversible pH-dependent anodic wave with current controlled by adsorption. Complexes of MGN with β-cyclodextrin (β-CD) were prepared and their formation was confirmed by UV-vis spectroscopy and electrochemical experiments, using a self-assembled monolayer of cyclodextrin on a gold electrode. The association constant of MGN:β-CD complexes was estimated by the Benesi-Hildebrand method, based on the spectrophotometric quantification of free β-CD and by the direct method using cyclic voltammetry and the Langmuir isotherm. PM IRRAS experiments corroborated the inclusion process based on the observation of the corresponding peaks in the spectra of the samples. MGN was quantified using a simple electrochemical method based on a β-CD incorporated carbon nanotube (CNT)-modified electrode (β-CDCNT). The presence of β-CD led to a 10-fold lower detection limit than that obtained with a CNT-modified electrode. © 2010 Elsevier Ltd. All rights reserved. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00134686_v56_n2_p797_Ferreira http://hdl.handle.net/20.500.12110/paper_00134686_v56_n2_p797_Ferreira |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
β-Cyclodextrin Apparent formation constant Carbon-nanotube modified electrodes Mangiferin PM IRRAS Anodic waves Association constant Benesi-Hildebrand Cd complex Current-controlled Differential pulse voltammetry Direct method Electrochemical behaviors Electrochemical experiments Electrochemical investigations ELectrochemical methods Formation constants Glassy carbon electrodes Gold electrodes Host guest interactions Langmuir isotherm Lower detection limit Mangiferin Modified electrodes Natural antioxidants PH-dependent PM-IRRAS UV-vis spectroscopy Voltammograms Adsorption Carbon nanotubes Complexation Drug interactions Electrodes Glass membrane electrodes Glassy carbon Gold compounds Self assembled monolayers Ultraviolet spectroscopy Cyclic voltammetry |
| spellingShingle |
β-Cyclodextrin Apparent formation constant Carbon-nanotube modified electrodes Mangiferin PM IRRAS Anodic waves Association constant Benesi-Hildebrand Cd complex Current-controlled Differential pulse voltammetry Direct method Electrochemical behaviors Electrochemical experiments Electrochemical investigations ELectrochemical methods Formation constants Glassy carbon electrodes Gold electrodes Host guest interactions Langmuir isotherm Lower detection limit Mangiferin Modified electrodes Natural antioxidants PH-dependent PM-IRRAS UV-vis spectroscopy Voltammograms Adsorption Carbon nanotubes Complexation Drug interactions Electrodes Glass membrane electrodes Glassy carbon Gold compounds Self assembled monolayers Ultraviolet spectroscopy Cyclic voltammetry Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| topic_facet |
β-Cyclodextrin Apparent formation constant Carbon-nanotube modified electrodes Mangiferin PM IRRAS Anodic waves Association constant Benesi-Hildebrand Cd complex Current-controlled Differential pulse voltammetry Direct method Electrochemical behaviors Electrochemical experiments Electrochemical investigations ELectrochemical methods Formation constants Glassy carbon electrodes Gold electrodes Host guest interactions Langmuir isotherm Lower detection limit Mangiferin Modified electrodes Natural antioxidants PH-dependent PM-IRRAS UV-vis spectroscopy Voltammograms Adsorption Carbon nanotubes Complexation Drug interactions Electrodes Glass membrane electrodes Glassy carbon Gold compounds Self assembled monolayers Ultraviolet spectroscopy Cyclic voltammetry |
| description |
The electrochemical behavior of mangiferin (MGN), a natural antioxidant compound, is examined using cyclic and differential pulse voltammetry in a protic medium on a glassy carbon electrode. The voltammograms exhibit a single irreversible pH-dependent anodic wave with current controlled by adsorption. Complexes of MGN with β-cyclodextrin (β-CD) were prepared and their formation was confirmed by UV-vis spectroscopy and electrochemical experiments, using a self-assembled monolayer of cyclodextrin on a gold electrode. The association constant of MGN:β-CD complexes was estimated by the Benesi-Hildebrand method, based on the spectrophotometric quantification of free β-CD and by the direct method using cyclic voltammetry and the Langmuir isotherm. PM IRRAS experiments corroborated the inclusion process based on the observation of the corresponding peaks in the spectra of the samples. MGN was quantified using a simple electrochemical method based on a β-CD incorporated carbon nanotube (CNT)-modified electrode (β-CDCNT). The presence of β-CD led to a 10-fold lower detection limit than that obtained with a CNT-modified electrode. © 2010 Elsevier Ltd. All rights reserved. |
| title |
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| title_short |
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| title_full |
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| title_fullStr |
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| title_full_unstemmed |
Electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| title_sort |
electrochemical investigations into host-guest interactions of a natural antioxidant compound with β-cyclodextrin |
| publishDate |
2010 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00134686_v56_n2_p797_Ferreira http://hdl.handle.net/20.500.12110/paper_00134686_v56_n2_p797_Ferreira |
| _version_ |
1768545676435652608 |